新型促透剂DMI在化妆品领域应用研究  

Research on the Application of Novel Penetration Enhancer DMI in the Cosmetics Industry

作　　者：张威 胡纯秋 陈剑晖 ZHANG Wei;HU Chunqiu;CHEN Jianhui(Guangzhou Duanmu Biotechnology Co.,Ltd.,Guangzhou 510000,China;Anhui Medical University,Hefei 230000,China;Shenzhen Yusu Biotechnology Co.,Ltd.,Shenzhen 518115,China)

机构地区：[1]广州端木生物科技有限公司,广东广州510000 [2]安徽医科大学,安徽合肥230000 [3]深圳市羽素生物科技有限公司,广东深圳518115

出　　处：《化工管理》2024年第29期91-95,共5页Chemical Management

摘　　要：化妆品引入活性成分促进透皮吸收已逐步普及,透皮吸收的效果将直接影响到化妆品的效果。文章分析了化妆品活性成分的促渗透原理,并对新型促透剂异山梨醇酐二甲醚(DMI)的促透原理和性能进行了探究,并进一步采取荧光素钠渗透法对DMI的促渗透效果开展了实验验证,以期为化妆品新型促透剂的研发提供新的思路和方向。The introduction of active ingredients in cosmetics to enhance transdermal absorption has gradually become prevalent,and the effectiveness of transdermal absorption directly impacts the performance of cosmetics.This article analyzes the principles of promoting penetration of active ingredients in cosmetics and delves into the penetration-enhancing mechanism and properties of the novel penetration enhancer,dimethyl isosorbide(DMI).Furthermore,a fluorescein sodium permeation method is employed to experimentally verify the penetration-enhancing effect of DMI,aiming to provide new insights and directions for the development of novel penetration enhancers in the cosmetics industry.

关 键 词：化妆品 活性成分 促透剂 DMI 

分 类 号：TQ658[化学工程—精细化工]