缺血预处理对冠状动脉介入术围手术期桡动脉并发症的影响  

Influence of ischemic preconditioning on radial artery complications during perioperative period of coronary intervention

作　　者：王蕊 欧阳琳 张欣 陈游洲 Wang Rui;Ouyang Lin;Zhang Xin;Chen Youzhou(Department of CCU,Beijing Jishuitan Hospital,Capital Medical University,Beijing 100096,China;Department of Interventional,Beijing Jishuitan Hospital,Capital Medical University,Beijing 100096,China)

机构地区：[1]首都医科大学附属北京积水潭医院CCU,北京100096 [2]首都医科大学附属北京积水潭医院介入科,北京100096

出　　处：《血管与腔内血管外科杂志》2024年第8期911-914,924,共5页Journal of Vascular and Endovascular Surgery

摘　　要：目的探讨缺血预处理对冠状动脉介入术围手术期桡动脉并发症的影响。方法收集2019年2月至2023年4月于首都医科大学附属北京积水潭医院接受冠状动脉介入术的193例冠状动脉粥样硬化性心脏病(CHD)患者的临床资料,按照干预方法的不同将其分为干预组(n=89)和对照组(n=104),比较两组患者冠状动脉介入术围手术期桡动脉并发症发生率。结果住院期间共发生桡动脉并发症65例,其中,干预组患者桡动脉并发症总发生率为25.8%(23/89),对照组患者为40.4%(42/104),两组比较,差异有统计学意义(P﹤0.05)。干预组患者桡动脉痉挛、狭窄发生率均低于对照组患者,差异均有统计学意义(P﹤0.05)。两组患者穿刺部位出血、迷走神经反射发生率比较,差异均无统计学意义(P﹥0.05)。干预组患者发生2种桡动脉并发症的比例低于对照组患者,差异有统计学意义(P﹤0.05)。结论缺血预处理可以显著降低冠状动脉介入术围手术期桡动脉并发症发生率,值得临床推广。Objective To investigate the effect of ischemic preconditioning on radial complications during perioperative period of coronary intervention.Method Clinical data of 193 patients with coronary atherosclerotic heart disease(CHD)who underwent coronary intervention in Beijing Jishuitan Hospital,Capital Medical University from February 2019 to April 2023 were collected and divided into intervention group(n=89)and control group(n=104)according to different intervention methods.The incidence of radial artery complications during perioperative period of coronary intervention was compared between the two groups.Result A total of 65 cases of radial artery complications occurred during hospitalization,of which the total incidence of radial artery complications was 25.8%(23/89)in the intervention group and 40.4%(42/104)in the control group,the difference between the two groups was statistically significant(P<0.05).The incidence of radial artery spasm and stenosis in intervention group were lower than those in control group,the differences were statistically significant(P<0.05).There were no significant differences in the incidence of puncture site bleeding and vagal reflex between two groups(P>0.05).The proportion of two radial artery complications in the intervention group was lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion Ischemic preconditioning can significantly reduce the incidence of radial complications during perioperative period of coronary intervention,which is worthy of clinical promotion.

关 键 词：缺血预处理 冠状动脉介入术 桡动脉 并发症 

分 类 号：R543[医药卫生—心血管疾病]