莱菔硫烷对脂毒性致肾损伤保护作用的研究进展  

Research Advances in the Protective Effect of Sulforaphane on Renal Injury Induced by Lipid Toxicity

作　　者：张春梅 伍春婷 牙甫礼 ZHANG Chunmei;WU Chunting;YA Fuli(School of Public Health,Dali University,Dali 671000,China)

机构地区：[1]大理大学公共卫生学院,云南大理671000

出　　处：《现代食品》2024年第17期42-44,共3页Modern Food

基　　金：2024年度云南省基础研究专项面上项目“莱菔硫烷经cAMP/PKA上调PINK1介导的线粒体自噬途径抑制高糖诱导血小板活化的作用研究”(202401AT070081)。

摘　　要：莱菔硫烷(Sulforaphane,SFN)是一种天然的异硫氰酸盐类化合物,广泛存在于西兰花等十字花科蔬菜中,具有抗肿瘤、抗氧化、抗炎等多种生物活性。脂毒性导致的肾损伤是慢性肾病的重要原因,本文概括SFN对脂毒性致肾损伤的改善作用,为研究十字花科蔬菜防治肾损伤提供理论基础。Sulforaphane(SFN)is a natural isothiocyanate compound that enriched in various cruciferous vegetables including broccoli,and exists multiple bioactivities including anti-cancer,anti-oxidant and anti-inflammtion.Lipotoxicity-induced renal injury is the main cause for chronic kidney disease.This article reviews the protective effect of SFN on lipotoxicity-induced renal injury and thus provides a theoretical basis for studying the prevention and treatment of kidney injury by cruciferous vegetables.

关 键 词：脂毒性 肾损伤 莱菔硫烷 十字花科蔬菜 

分 类 号：G353.11[文化科学—情报学]