吴茱萸挥发油的GC-MS分析  

GC-MS Analysis of the Volatile Oil of Euodiae Fructus

作　　者：尹丽 彭苑霞 陆华强 杨秋燕 曹亮启 Yin Li;Peng Yuanxia;Lu Huaqiang;Yang Qiuyan;Cao Liangqi(Guangzhou Huashang Vocational College,Guangzhou 511300,China;Key Laboratory of Chinese Medical Resources from Lingnan,Ministry of Education,Guangzhou 510700,China)

机构地区：[1]广州华商职业学院,广东广州511300 [2]广州中医药大学岭南中药资源教育部重点实验室,广东广州510700

出　　处：《广东化工》2024年第19期178-179,191,共3页Guangdong Chemical Industry

基　　金：广东省中药材产业化基地建设项目“吴茱萸规范化、规模化、产业化种植基地”(粤工信消费函[2021]72号);2022年度“科教研繁荣计划”课题(KY2022018)。

摘　　要：为分析不同干燥方法处理的吴茱萸挥发油成分,采用水蒸气蒸馏法提取烘干、晒干处理的吴茱萸的挥发油,利用气相色谱-质谱联用技术(GC-MS)检测两者挥发油成分,采用面积归一化法计算各成分的相对含量;结果表明两者挥发油的提取率分别为0.21%和0.29%;从两者挥发油中鉴定到的交集化合物有65种,但含量差异较大;两者中相对含量前三的化合物相同,分别是β-榄香烯、β-石竹烯和大根香叶烯D;其中含量最高的β-榄香烯具有良好的抗肿瘤作用。本研究为吴茱萸挥发油的开发利用提供了实验基础。In order to analyze the volatile oil components of Euodiae Fructus treated by different drying methods,the volatile oil of oven-drying and sun-drying samples was extracted by water steam distillation,detected by GC-MS method and the relative content of each component was calculated by area normalization method;The results show that the extraction rate of the volatile oils was 0.21%and 0.29%,respectively;65 overlapping compounds were identified from both volatile oil,but the content differences were significant.The top three compounds with the highest relative content in both samples were the same,includingβ-Elemene,Caryophyllene and Germacrene D;The highest content,β-Elemene,shows good anti-tumor effect.This study provides the experiental basis for the development and utilization of volatile oil from Euodiae Fructus.

关 键 词：吴茱萸 挥发油 GC-MS Β-榄香烯 β-石竹烯 大根香叶烯D 

分 类 号：R284.1[医药卫生—中药学]