超声检查参数及血栓弹力图在房颤患者抗血栓药物治疗中的相关性  

Correlation between ultrasound examination parameters and thromboelastogram in antithrombotictreatment for patients with atrial fibrillation

作　　者：汪志新 钟易敏 刘涛 Wang Zhixin;Zhong Yimin;Liu Tao(Department of Cardiology,Wuhan Red Cross Hospital,Wuhan 430000,China)

机构地区：[1]武汉市红十字会医院心血管内科,武汉430000

出　　处：《中国医学装备》2024年第10期86-89,共4页China Medical Equipment

基　　金：湖北省卫健委2022年度联合基金(WJ2022H0120)。

摘　　要：目的:分析房颤患者抗血栓药物使用与超声检查结果及血栓弹力图变化特征的相关性。方法:选取2021年1月至2022年10月武汉市红十字会医院收治的80例房颤患者,根据血栓检查有无血栓形成将患者分为观察组(26例,有血栓形成)和对照组(64例,无血栓形成)。所有患者均使用抗血栓药物治疗,并在治疗前后进行超声与血栓弹力图检查,比较两组检查结果的差异,并通过相关性分析各指标与房颤患者抗血栓药物使用效果的相关性。结果:两组患者治疗前超声心动图检查指标差异均无统计学意义(P>0.05),观察组治疗后左房射血分数、左室射血分数均低于对照组,差异均有统计学意义(t=5.325、5.285,P<0.05);两组治疗前血栓弹力图指标差异均无统计学意义(P>0.05),观察组治疗后血栓弹力图指标的反应时间(R)值(5.0±1.6)min、凝固时间(K)值(2.4±0.6)min均低于对照组(9.8±2.2和5.7±1.8)min,差异均有统计学意义(t=5.326、5.564,P<0.05)。相关性分析发现,左房射血分数、左室射血分数、R值及K值与房颤患者抗降低血栓形成风险,血栓药物使用效果与超声检查结果存在相关性(r=0.552、0.546、0.546、0.532,P<0.05)。结论:超声检查结果及血栓弹力图变化特征可指导房颤患者使用抗血栓药物,从而提高抗血栓治疗的获益率,改善患者的预后情况。Objective:To analyze the correlation between the use of antithrombotic drugs,results of ultrasound examination and the change characteristics of thromboelastogram in patients with atrial fibrillation.Methods:A total of 80 patients with atrial fibrillation who admitted to Wuhan Red Cross Hospital were selected from January 2021 to October 2022.According to with or without thrombosis in patients,they were divided into an observation group(with thrombosis,26 cases)and a control group(without thrombosis,64 cases).All patients were treated by using antithrombotic drugs.Both of two groups underwent ultrasound and thromboelastogram examinations before and after treatment.The difference of the examination results between the two groups were compared.The correlation analysis was adopted to analyze the correlation between each indicator and the curative effect of antithrombotic drugs in patients with atrial fibrillation.Results:There was no significant difference in examination indicators of echocardiogram between the two groups before treatment(P>0.05).After treatment,the left atrial ejection fraction and left ventricular ejection fraction of the observation group were significantly lower than those of the control group(t=5.325,5.285,P<0.05).The differences in the indicators of thromboelastogram between the two groups were not significant before treatment(t=1.325,1.425,P>0.05),respectively.After treatment,the response time(R value)[(5.0±1.6)min]and coagulation time(K value)[(2.4±0.6)min]of the observation group were significantly lower than(9.8±2.2)min and(5.7±1.8)min of the control group(t=5.326,5.564,P<0.05),and the differences were significant(t=5.362,5.564,P<0.05),respectively.The correlation analysis indicated that there were correlations between left atrial ejection fraction,left ventricular ejection fraction,R value,K value and the risks of anti-reducing thrombosis formation and the use effect of thrombotic drugs in patients with atrial fibrillation(r=0.552,0.546,0.546,0.532,P<0.05),respectively.Conclusion:The

关 键 词：房颤 抗血栓药物 超声参数 血栓弹力图 

分 类 号：R445.1[医药卫生—影像医学与核医学]