颅内生殖细胞肿瘤放疗后患者体外受精-胚胎移植助孕成功1例  

A successful case of in vitro fertilization and embryo transfer pregnancy in patients with intracranial germ cell tumors after radiotherapy

作　　者：于颖[1] 杨慧琳 李颖哲 张佳欣 潘袁[1] Yu Ying;Yang Huilin;Li Yingzhe;Zhang Jiaxin;Pan Yuan(Reproductive Center,Prenatal Diagnosis Center,the First Hospital of Jilin University,Changchun 130000,China)

机构地区：[1]吉林大学第一医院生殖中心·产前诊断中心,长春130000

出　　处：《中华生殖与避孕杂志》2024年第9期952-954,共3页Chinese Journal of Reproduction and Contraception

摘　　要：颅内生殖细胞肿瘤(intracranial germ cell tumours,iGCTs)放疗后可能导致女性患者出现低促性腺激素性闭经而不孕。本案例探讨iGCTs放疗史患者助孕治疗及助孕方案的选择。对1例iGCTs放疗史患者使用注射用人尿促性素及注射用重组人促黄体生成素促排卵后,行新鲜胚胎移植后成功妊娠,并于孕39+5周时行剖宫产终止妊娠,娩一健康女婴。此助孕方案可为相似患者的治疗提供参考,优化临床决策。After radiotherapy of intracranial germ cell tumors(iGCTs),female patients may suffer from hypogonadotropic amenorrhea and infertility.In this case,we investigated the selection of pregnancy assistance treatment and pregnancy assistance program for patients with iGCTs radiotherapy history.This case reported a patient with a history of radiotherapy for iGCTs who underwent fresh embryo transfer and successful pregnancy after ovulation induction with injectable human menopausal gonadotropin and recombinant human luteinizing hormone.The patient underwent cesarean section at 39+5 weeks of gestation and delivered a healthy female infant.This pregnancy assistance scheme can provide reference for the treatment of similar patients and optimize clinical decision-making.

关 键 词：受精 体外 胚胎移植 颅内生殖细胞肿瘤 放疗 

分 类 号：R714.8[医药卫生—妇产科学]