正中神经电刺激对脑损伤患者昏迷唤醒的研究进展  

Research progress on median nerve electrical stimulation for awakening comatose patients with brain injury

作　　者：安乐 邵瑞[1] 王兴圣 唐子人[1] An Le;Shao Rui;Wang Xingsheng;Tang Ziren(Department of Emergency Medicine,Beijing Chao-Yang Hospital,Capital Medical University,Beijing 100020,China)

机构地区：[1]首都医科大学附属北京朝阳医院急诊医学科,北京100020

出　　处：《中华危重病急救医学》2024年第9期997-1000,共4页Chinese Critical Care Medicine

基　　金：国家自然科学基金(82072136);首都卫生发展科研专项(2022-1-2032);北京市卫健委高层次公共卫生技术人才建设项目(学科带头人01-01)。

摘　　要：随着医学的发展, 颅脑损伤患者的救治率逐渐提升, 更多的生命被成功挽救, 但因此产生的昏迷患者逐渐增多, 持续的医疗照护增加了家庭及社会的经济负担, 对昏迷患者进行促醒的意义重大。正中神经电刺激(MNS)作为一种无创的脑刺激技术, 已广泛应用于临床促醒治疗, 多项临床研究证实了此项技术的效果。本文从昏迷机制、正中神经通路、MNS的促醒机制、MNS的临床应用、电刺激的参数设置及神经功能评估等方面, 总结该技术的研究进展。With the development of medicine,the survival rate of patients with traumatic brain injury has gradually increased,and more lives have been successfully saved.However,the number of comatose patients has also risen,leading to prolonged medical care that increases economic burdens on families and society.The awakening of comatose patients is of great significance.As a non-invasive brain stimulation technique,median nerve electrical stimulation(MNS)has been widely used in clinical awakening therapy,and multiple clinical studies have confirmed the effectiveness of this technology.This article summarizes the research progress of this technology from the aspects of coma mechanism,median nerve pathway,awakening mechanism of MNS,clinical application of MNS,parameter setting of electrical stimulation,and neurological function evaluation.

关 键 词：正中神经 正中神经电刺激 脑损伤 昏迷 促醒 

分 类 号：R651.15[医药卫生—外科学]