自拟益气补虚方对冠心病急诊经皮冠状动脉介入术后心脾两虚型心悸的临床研究  

A Clinical Study on the Treatment of Heart and Spleen Deficiency Palpitations in the Late Stage after PPCI Surgery of Coronary Heart Disease

作　　者：谢悦悦 陈光瑞 张天宇 刘韩 XIE Yueyue;CHEN Guangrui;ZHANG Tianyu;LIU Han(Taihe Traditional Chinese Medicine Hospital Affiliated of Anhui University of Chinese Medicine,Anhui Fuyang 236600,China)

机构地区：[1]安徽中医药大学附属太和中医院,安徽阜阳236000

出　　处：《中医药临床杂志》2024年第10期1943-1947,共5页Clinical Journal of Traditional Chinese Medicine

基　　金：安徽中医药大学临床科研项目计划(2021LCTH13)。

摘　　要：目的:研究自拟益气补虚方对冠心病急诊经皮冠状动脉介入(Interventional Percutaneous Coronary Intervention,PPCI)治疗术后心脾两虚型心悸的临床疗效。方法:收集整理并分析太和县中医院心内科2022年1月—2022年10月入院的急性心肌梗死并成功完成PPCI术患者,术后恢复期中医辨证属于心脾两虚型心悸,按照随机分组分为对照组(31例)和治疗组(31例)。对照组患者采用冠心病急性心肌梗死PPCI术后常规西药治疗,治疗组患者在对照组的基础上加服自拟益气补虚汤,根据患者个人情况酌情加减,两组疗程均为4周。比较两组患者治疗前后心脏彩超左室射血分数、每搏输出量、左室舒张末期内径、自觉心悸症状、动态心电图、中医证候积分水平。结果:治疗前两组患者每一项评分比较,差异不具有统计学意义(P>0.05),治疗后观察组心脏彩超左室射血分数高于对照组,左室舒张末期内径增大值低于对照组,中医证候改善情况优于对照组,自觉心悸症状缓解程度优于对照组,动态心电图结果发生心率失常概率少于对照组,比较差异有统计学意义(均P<0.05);治疗后两组心脏彩超每搏输出量比较差异无统计学意义(P>0.05)。结论:自拟益气补虚方治疗能明显缓解冠状动脉介入术术后心脾两虚型心悸临床症状,减少冠状动脉介入术术后心律失常的发生,延缓心肌损伤进程,从而促进术后恢复期康复,提高患者生活质量。Objective:To study the clinical efficacy of self-prescribed Yiqi Buxu prescription in the treatment of postoperative palpitations of heart and spleen deficiency type after emergency percutaneous coronary intervention(PPCI)for coronary heart disease.Methods:The patients with acute myocardial infarction who were admitted to the Department of Cardiology of Taihe County Hospital of Traditional Chinese Medicine from January 2022 to October 2022 and successfully completed PPCI were collected and analyzed.The patients were classified into the control group(31 cases)and the treatment group(31 cases)according to the syndrome differentiation of Chinese medicine in the postoperative recovery period.The patients in the control group were treated with conventional western medicine after PPCI for acute myocardial infarction of coronary heart disease.The patients in the treatment group took self-prescribed Yiqi Buxu decoction on the basis of the control group,and the amount was adjusted according to the individual conditions of the patients.The treatment course of both groups was 4 weeks.The two groups were compared before and after treatment in terms of left ventricular ejection fraction,stroke volume,left ventricular end-diastolic diameter,subjective palpitation symptoms,dynamic electrocardiogram,and TCM syndrome score.Results:There was no significant difference in each score between the two groups before treatment(P>0.05).After treatment,the left ventricular ejection fraction of the observation group was higher than that of the control group,the increase of left ventricular end-diastolic diameter was lower than that of the control group,the improvement of TCM syndrome was better than that of the control group,the degree of relief of subjective palpitation symptoms was better than that of the control group,and the probability of arrhythmia in dynamic electrocardiogram results was less than that of the control group,and the difference was statistically significant(P<0.05);there was no significant difference in stroke volume be

关 键 词：冠状动脉介入术术后 心悸 心脾两虚证 益气补虚方 

分 类 号：R256.2[医药卫生—中医内科学]