2,3-二氯-1,4-萘醌的合成工艺  

Study on Synthesis Technology of 2,3-Dichloro-1,4-Naphthoquinone

作　　者：夏孔浩 丁军委[1] 单玉领 张欣磊 XIA Konghao;DING Junwei;SHAN Yuling;ZHANG Xinlei(College of Chemical Engineering,Qingdao University of Science and Technology,Qingdao 266042,China)

机构地区：[1]青岛科技大学化工学院,山东青岛266042

出　　处：《青岛科技大学学报（自然科学版）》2024年第5期57-61,共5页Journal of Qingdao University of Science and Technology:Natural Science Edition

基　　金：山东省重点研发计划项目(2019GSF109055)。

摘　　要：研究了以1,4-萘醌为原料,催化氯化制备2,3-二氯-1,4-萘醌的反应机理及合成工艺优化。研究发现该氯化反应为酸催化反应机理,氯化氢为有效的1,4-萘醌氯化催化剂。通过工艺优化确定了最佳合成条件为:反应温度75℃,催化剂用量1.5mL,溶剂用量80 mL,原料加入量为7.5 g,通氯速度为15mL·min^(-1),反应时间为1.5~2 h,产品纯度大于99.5%。母液经多次套用后产品收率达到91%~93%,产品纯度均达到优等品级别(≥99.0%)。The reaction mechanism and synthesis process optimization of 2,3-dichloro-1,4-naphthoquinone prepared by catalytic chlorination with 1,4-naphthoquinone as raw materi-al,hydrogen chloride as catalyst and chlorobenzene as solvent were studied.The optimum synthesis conditions were determined as follows:reaction temperature 75℃,catalyst dosage 1.5 mL,solvent dosage 80 mL,raw material dosage 7.5 g,chlorination speed 15 mL·min^(-1),reaction time 1.5-2 h,product purity more than 99.5%.After repeated application of mother liquor,the yield of the product reached 91%-93%and the purity of the product was≥99.0%.

关 键 词：2 3-二氯-1 4-萘醌 1 4-萘醌 酸催化 

分 类 号：TQ612.1[化学工程—精细化工]