细胞力学2023年度研究进展  

Research Progress of Cellular Mechanics in 2023

作　　者：朱鸿源 王琎 苗润 林敏[1] ZHU Hongyuan;WANG Jin;MIAO Run;LIN Min(The Key Laboratory of Biomedical Information Engineering of Ministry of Education,Bioinspired Engineering and Biomechanics Center(BEBC),School of Life Science and Technology,Xi’an Jiaotong University,Xi’an 710049,China)

机构地区：[1]西安交通大学生命科学与技术学院,生物信息工程教育部重点实验室,仿生工程与生物力学研究所,西安710049

出　　处：《医用生物力学》2024年第5期787-795,共9页Journal of Medical Biomechanics

基　　金：国家自然科学基金项目(12202345,12372316,12022206);中国博士后科学基金项目(2022M722534);中央高校基本科研业务费专项资金(xzy012024081)。

摘　　要：细胞力学研究在近年来迅速发展,揭示了细胞如何通过感知和响应外界力学环境来调节其功能和行为。2023年,细胞力学领域在理解细胞自身的力学特性、对固体和流体环境的力学感知、在动态力学条件下的适应性方面取得了显著突破。同时,先进的测量技术和力学模型为研究提供了新的工具。这些成果加深了对生理和病理过程的认识,并为疾病的诊断、预防和干预手段提供新的思路。本文综述了2023年度华人学者在细胞力学领域的研究进展,探讨其在不同生物过程中所展现的力学机制。Research in cellular mechanics has rapidly advanced in recent years,uncovering how cells regulate their functions and behaviors by sensing and responding to mechanical cues from their environment.In 2023,significant breakthroughs were made in understanding the mechanical properties of cells,their mechanosensing of solid and fluid environments,and their adaptability under dynamic mechanical conditions.Meanwhile,advanced measurement techniques and mechanical models have provided new tools for investigation.These achievements have deepened the understanding of physiological and pathological processes,offering new approaches for disease diagnosis,prevention,and intervention.This review summarizes the research progress by Chinese scholars in cellular mechanics and explores the mechanical mechanisms exhibited in various biological processes in the year 2023.

关 键 词：力学生物学 细胞力学性能 力信号转导 力学模型 

分 类 号：R318.01[医药卫生—生物医学工程]