上海市35~75岁社区居民心血管病危险因素聚集与静息心率升高的关联性研究  

Association between cardiovascular risk factor clustering and elevated resting heart rate among 35-75 years old residents from community,Shanghai

作　　者：王英全 浦震梅 杨群娣[1] 郑杨[1] 刘丹妮 王玉琢 施燕[1] 顾海雁[2] WANG Ying-quan;PU Zhen-mei;YANG Qun-di;ZHENG Yang;LIU Dan-ni;WANG Yu-zhuo;SHI Yan;GU Hai-yan(Institute of Chronic Non communicable Diseases and Injury Prevention and Control,Shanghai Center for Disease Control and Prevention,Shanghai 200050,China;不详)

机构地区：[1]上海市疾病预防控制中心慢性非传染性疾病与伤害防治所,上海200050 [2]上海市徐汇区疾病预防控制中心

出　　处：《现代预防医学》2024年第20期3657-3663,共7页Modern Preventive Medicine

基　　金：上海市加强公共卫生体系建设三年行动计划(2023-2025年)(GWVI-8);上海市加强公共卫生体系建设三年行动计划(2023-2025年)公共卫生重点学科建设项目(GWVI-11.1-22);国家卫生健康委重大公共卫生项目:心血管病高危人群早期筛查与综合干预(财社【2014】37号)。

摘　　要：目的探讨上海市35~75岁社区居民心血管病危险因素聚集与静息心率升高的关联性。方法研究基于国家“心血管病高危人群早期筛查与综合干预项目”,于2017—2019年对上海市8个区35~75岁常住居民开展问卷调查、体格检查与生化检测。采用R 4.2.2统计软件,通过Kruskal-Wallis检验和Cochran-Mantel-Haenszel检验进行组间比较,多元logistic回归探索心血管病常见危险因素聚集数量、危险因素组合与静息心率升高的关联性。结果纳入87934名调查对象,平均年龄为(59.1±9.7)岁,暴露于1、2、3和≥4个危险因素者静息心率升高风险OR值(95%CI)分别为1.42(1.36~1.47)、1.70(1.53~1.77)、1.94(1.84~2.05)和2.17(1.99~2.36)。亚组分析结果表明,中青年女性暴露(35~44岁组)≥4个危险因素者与静息心率升高的关联效应较高(OR=3.77,95%CI:2.10~4.27)。危险因素组合中,代谢危险因素较多时,静息心率升高的风险较高。结论静息心率或可作为多个心血管病危险因素累积效应的一个简单、实用的指标,有助于早期识别相对健康人群中的心血管高风险个体,特别是中青年人群中的心血管病高风险个体,从而尽早进行综合干预。Objective To explore the association between the accumulation of cardiovascular risk factors and the elevated resting heart rate in community residents aged 35-75 years in Shanghai Methods Participates were obtained from the China PEACE Million Persons Projects.8 districts in Shanghai were selected from 2017 to 2019,and the screening was carried out between adults aged 35 to 75 years in communities.Questionnaires,physical examinations and laboratory tests were conducted.The Kruskal-Wallis test and Cochran-Mantel-Haenszel test were used to compare groups by using R 4.2.2 software.Multivariate logistic regression was performed to explore the correlation between the number of common risk factors for cardiovascular diseases,the combination of different risk factors and elevated resting heart rate.Results Among 87934 participants,the mean age was 59.1±9.7 years.Compared with the group with no risk factors,the OR(95%CI)for elevated resting heart rate for the groups with 1,2,3 and≥4 risk factor were 1.42(1.36-1.47)、1.70(1.53-1.77)、1.94(1.84-2.05)and 2.17(1.99-2.36),respectively.The risk of elevated RHR was the most strongly influenced by the cardiovascular risk factor clustering number in the female group aged 35 to 44 with≥4 risk factors,and the OR(95%CI)was 3.77(2.10-4.27).In the combination of risk factors,more metabolic risk factors were associated with a higher risk of elevated resting heart rate.Conclusion Resting heart rate may serve as a simple and practical indicator of the cumulative effect of multiple cardiovascular risk factors,which can help early identification of individuals at high cardiovascular risk in relatively healthy people,so as to enable early intervention.

关 键 词：心血管病疾病 静息心率 危险因素聚集 

分 类 号：R54[医药卫生—心血管疾病]