综合护理方案在中重度痤疮红蓝光治疗期间的应用  

Application of comprehensive nursing scheme in the treatment of moderate and severe acne with red and blue light

作　　者：王倩 王雪寒 范雅兰 李静[3] WANG Qian;WANG Xue-han;FAN Ya-lan;LI Jing(Department of Dermatology,the Second People's Hospital of Henan Province,Zhengzhou 450000,Henan,CHINA;Outpatient Infusion Room,the Second People's Hospital of Henan Province,Zhengzhou 450000,Henan,CHINA;Department of Infectious Diseases,Henan Provincial People's Hospital,Zhengzhou 450000,Henan,CHINA)

机构地区：[1]河南省第二人民医院皮肤科,河南郑州450000 [2]河南省第二人民医院门诊输液室,河南郑州450000 [3]河南省人民医院感染性疾病科,河南郑州450000

出　　处：《海南医学》2024年第20期3021-3026,共6页Hainan Medical Journal

基　　金：河南省医学科技攻关联合共建项目(编号:LHGJ20220002)。

摘　　要：目的研究综合护理方案在中重度痤疮红蓝光治疗期间的应用效果。方法选取2021年1月至2023年10月在河南省第二人民医院皮肤科门诊治疗的95例中重度痤疮患者作为研究对象,按随机数表法分为对照组47例和观察组48例,对照组进行常规护理,观察组基于对照组进行综合护理方案,两组护理干预时间均为8周。比较两组患者干预8周时的临床效果,以及干预前和干预8周时的皮损评分、皮肤生理指标[皮肤弹性指数(R2)、红斑指数(E1)、皮肤颜色指数黑素指数(M1)、经表皮失水率(TEWL)及角质层含水量]、抑郁自评量表、焦虑自评量表及皮肤病生活质量评分量表评分;比较两组患者治疗期间的不良反应发生情况。结果观察组患者的治疗总有效率为72.92%,明显高于对照组的48.94%,差异有统计学意义(P<0.05);干预前,两组患者的皮损评分、皮肤生理指标、抑郁自评量表(SDS)、焦虑自评量表(SAS)及皮肤病生活质量评分量表评分比较差异均无统计学意义(P>0.05);干预8周时,两组患者的皮损评分均明显降低,且观察组患者的皮损评分为(5.27±1.12)分,明显低于对照组的(8.92±1.43)分,差异均有统计学意义(P<0.05);干预8周时,两组患者的R2均增加,EI及TEWL均降低,且观察组患者的R2为0.86±0.14,明显高于对照组的0.78±0.11,观察组患者的E1、TEWL分别为365.09±31.15、(10.78±2.19)g/hm^(2),明显低于对照组的387.21±28.06、(13.02±2.06)g/hm^(2),差异均有统计学意义(P<0.05),但两组患者干预前后的MI、角质层含水量比较差异均无统计学意义(P>0.05);干预8周时,两组患者的SDS,SAS及皮肤病生活质量评分量表评分均明显降低,且观察组患者的SDS、SAS及皮肤病生活质量量表评分分别为(41.86±4.26)分、(40.39±4.18)分、(3.39±0.44)分,明显低于对照组的(46.49±4.50)分、(45.33±4.72)分、(6.91±0.82)分,差异均有统计学意义(P<0.05);两组患者治疗期间均无明显Objective To study the application effect of comprehensive nursing scheme in the treatment of moderate and severe acne with red and blue light.Methods Ninety-five patients with moderate to severe acne who were treated in the Outpatient Department of Dermatology,the Second People's Hospital of Henan Province from January 2021 to October 2023 were selected and randomly divided into a control group of 47 cases and a study group of 48 cases using a random number table method.Patients in the control group received routine nursing care,while those in the observation group received comprehensive nursing scheme based on routine nursing care,all for 8 weeks.The clinical effects after intervention for 8 weeks were compared between the two groups of patients,as well as the skin lesion scores,skin physiological indicators(skin elasticity index[R2],erythema index[EI],skin color index,melanin index[MI],transepidermal water loss[TEWL],and water content of stratum corneum),Self-rating Depression Scale(SDS),Self-rating Anxiety Scale(SAS),and Quality of Life Scale for skin diseases before and after 8 weeks of intervention.The incidence rates of adverse reactions during treatment were also compared.Results The total effective rate of the study group was 72.92%,which was significantly higher than 48.94%of the control group(P<0.05).Before the intervention,there was no significant difference in skin lesion score,skin physiological index,SDS,SAS,and Quality of Life Scale for skin diseases between the two groups(P>0.05).After 8 weeks of intervention,the skin lesion scores of the two groups decreased significantly,and the score of the observation group was(5.27±1.12)points,which was significantly lower than(8.92±1.43)points of the control group,with statistically significant differences(P<0.05).After 8 weeks of intervention,R2 of patients in both groups increased,and the R2 in the observation group was 0.86±0.14,which was significantly higher than 0.78±0.11 of the control group;the EI and TEWL of patients in both groups decreased,and

关 键 词：痤疮 中重度 红蓝光 综合护理 皮损评分 

分 类 号：R473.75[医药卫生—护理学]