叔丁基亚磺酰胺类过渡金属手性催化剂的研究进展  

Research Progress on Transition Metal Catalysts of tert-Butyl Sulfinamide

作　　者：张子豪 靳博宇 刘姗姗 ZHANG Zi-hao;JIN Bo-yu;LIU Shan-shan(College of New Materials and Chemical Engineering,Beijing Institute of Petrochemical Technology,Beijing 102617,China;Beijing Key Laboratory of Fuels Cleaning and Advanced Catalytic Emission Reduction Technology,Beijing Institute of Petrochemical Technology,Beijing 102617,China)

机构地区：[1]北京石油化工学院新材料与化工学院,北京102617 [2]北京石油化工学院燃料清洁与先进催化减排技术北京重点实验室,北京102617

出　　处：《分子催化（中英文）》2024年第5期483-501,I0004,共20页Journal of Molecular Catalysis(China)

基　　金：北京市属高等学校优秀青年人才培育计划项目(BPHR2203090);北京市科学技术协会青年人才托举工程(BYESS2023257);北京市大学生科学研究与创业行动计划(2022J00003)。

摘　　要：自1997年Ellman课题组首次合成并分离得到光学纯手性叔丁基亚磺酰胺以来,叔丁基亚磺酰胺就被广泛地应用于过渡金属催化剂的合成.由于叔丁基亚磺酰胺类过渡金属催化剂具有结构简单、易于合成、催化性能良好等优点,使其成为不对称催化领域的研究热点.国内外许多研究团队陆续设计、合成新型叔丁基亚磺酰胺类过渡金属催化剂,并研究其潜在应用价值.我们综述了将近十年来报道的叔丁基亚磺酰胺类过渡金属催化剂,根据配体配位原子、基团进行分类,分为叔丁基亚磺酰胺-硫配体、叔丁基亚磺酰胺-磷配体、叔丁基亚磺酰胺-烯烃配体以及其他叔丁基亚磺酰胺类配体(配位原子为S、N或S、O)4大类,并对它们的合成方法及应用进行了简要阐述.Since 1997,the Ellman research group has synthesized and separated optically pure chiral tert-butyl sulfinamide for the first time,which has been applied in the synthesis of transition metal catalysts.Due to the advantages of simple structure,easy synthesis,and good catalytic performance,transition metal catalysts based on tert-butyl sulfinamide have become a research hotspot in the field of asymmetric catalysis.Therefore,many research groups at home and abroad have been designing and synthesizing new tert-butyl sulfinamide transition metal catalysts,and study their potential application.In this review,we summarized the tert-butyl sulfinamide transition metal catalysts reported in the past ten years,which are classified according to the ligand coordination atoms and functional groups,and can be divided into four categories:tert-butyl sulfinamide-sulfur ligand,tertbutyl sulfinamide-phosphorus ligand,tert-butyl sulfinamide-olefin ligand,and other tert-butyl sulfinamide ligand(coordination atoms are S,N or S,O).The synthesis methods and applications of these catalysts are briefly described.

关 键 词：叔丁基亚磺酰胺 过渡金属催化剂 不对称合成 

分 类 号：O643.32[理学—物理化学]