不同生理条件下主动脉双叶机械心脏瓣膜血流动力学分析  

Hemodynamic analysis of aortic bileaflet mechanical heart valve under different physiologic conditions

作　　者：强彦[1,2] 张民祖 段天赐 祁亮[3] QIANG Yan;ZHANG Minzu;DUAN Tianci;QI Liang(College of Energy and Power Engineering,Lanzhou University of Technology,Lanzhou 730050,China;Key Laboratory of Advanced Pumps,Valves and Fluid Control System of the Ministry of Education,Lanzhou University of Technology,Lanzhou 730050,China;Department of Cardiovascular Surgery,the First Hospital of Lanzhou University,Lanzhou 730000,China)

机构地区：[1]兰州理工大学能源与动力工程学院,甘肃兰州730050 [2]兰州理工大学特种泵阀及流控系统教育部重点实验室,甘肃兰州730050 [3]兰州大学第一医院心血管外科,甘肃兰州730000

出　　处：《中国医学物理学杂志》2024年第10期1281-1288,共8页Chinese Journal of Medical Physics

基　　金：国家自然科学基金(51966010)。

摘　　要：采用计算流体动力学方法对不同生理条件下主动脉位置双叶机械心脏瓣膜下游的速度分布、涡演化、粘性剪切应力、雷诺剪切应力进行研究。收缩期峰值时,运动状态下血液射流较其他两种生理状态下更为强烈,最大血液流速为2.1 m/s。对于涡演化的分析表明3种生理状态下剪切层是比较明显的流动特征,在收缩期峰值时,血液与主动脉窦作用较为强烈。对于粘性剪切应力,当瓣叶完全打开时,瓣叶在瓣膜区阻碍了血液流过瓣膜,血流与瓣叶之间的相互作用导致了较高的剪切应力,3种生理状态下,观察到的最大粘性剪应力小于8 N/m^(2)。3种生理状态下观察到最大的雷诺剪切应力为700 N/m^(2)。本研究有助于为临床手术瓣膜选择以及术后康复提供理论依据。The velocity distribution,vortex evolution,viscous shear stress distribution and Reynolds shear stress distribution downstream of the aortic bileaflet mechanical heart valve are investigated under different physiological conditions using computational fluid dynamics method.At peak systole,the blood jet is more intense in the exercise state than in the other two states,with a maximum blood flow rate of 2.1 m/s.The analysis on vortex evolution shows that the shear layer is the obvious flow feature in the 3 physiological states and that the blood interacts more strongly with the aortic sinus at peak systole.For viscous shear stress,when the valve leaflets are fully open,the leaflets impede blood flow across the valve in the valvular region.The interaction between the blood flow and the valve leaflets results in high shear stress,and the maximum viscous shear stress observed in the 3 physiologic states is less than 8 N/m^(2).The maximum Reynolds shear stress observed in the 3 physiologic states is 700 N/m^(2).The study provides a theoretical basis for surgical valve selection and postoperative rehabilitation.

关 键 词：双叶机械心脏瓣膜 血流动力学 计算流体力学 涡演化 粘性剪切应力 雷诺剪切应力 

分 类 号：R318[医药卫生—生物医学工程] O368[医药卫生—基础医学]