荧光染色法快速诊断真菌性外耳道炎的意义  

Significance of rapid diagnosis of fungal otitis externa by fluorescence staining

作　　者：邓海燕 高兴强 郭宇峰 吴晓慧 钟连生 DENG Haiyan;GAO Xingqiang;GUO Yufeng;WU Xiaohui;ZHONG Liansheng(Department of Otolaryngology Head and Neck Surgery,Xiamen Children’s Hospital,Xiamen 361013,China)

机构地区：[1]厦门市儿童医院耳鼻咽喉头颈外科,福建厦门361013

出　　处：《中国耳鼻咽喉颅底外科杂志》2024年第5期95-97,102,共4页Chinese Journal of Otorhinolaryngology-skull Base Surgery

基　　金：厦门市小儿外科疾病重点实验室开放课题(CHP-2023-XKL-020)。

摘　　要：目的探讨荧光染色法快速诊断真菌性外耳道炎的临床意义。方法回顾性分析2021年1月-2023年12月在厦门市儿童医院耳鼻咽喉门诊疑诊的真菌性外耳道炎患儿30例,每例均行外耳道分泌物荧光染色法检查和真菌培养,比较荧光染色法检查和真菌培养检出的真菌感染阳性率。结果30例疑诊患儿中,荧光染色法检出真菌感染28例,真菌培养检出真菌感染26例,荧光染色法检测真菌性外耳道炎患儿的阳性率(93.3%)高于真菌培养法(86.7%),差异具有统计学意义(χ^(2)=0.04,P<0.05)。结论荧光染色法诊断真菌性外耳道炎的检出率更高,且操作更简便快捷,值得临床推广应用。Objective To explore the clinical significance of fluorescence staining in the rapid diagnosis of fungal otitis externa.Methods A retrospective analysis was performed on 30 children with suspected fungal otitis externa,who were diagnosed at the Otolaryngology Outpatient Clinic of Xiamen Children’s Hospital from January 2021 to December 2023.All cases were examined by external ear canal secretion fluorescence staining and fungal cultivation.The positive rate of fungal infection was compared between fluorescence staining and fungal cultivation.Results Of the 30 suspected children,28 cases were detected as fungal infections by fluorescence staining,and 26 cases were detected as fungal infections by fungal culture.The positive rate of fungal otitis externa was higher by fluorescence staining(93.3%)than by fungal cultivation method(86.7%),and the difference was statistically significant(χ^(2)=0.04,P<0.05).Conclusion The fluorescence staining method is high detection rate in diagnosing fungal otitis externa.And the operation is more simple and fast.It is worthy of clinical promotion and application.

关 键 词：真菌性外耳道炎 荧光染色法 真菌培养 

分 类 号：R764.11[医药卫生—耳鼻咽喉科]