血脂水平与认知障碍相关性的研究进展  

Research progress on correlation between lipid levels and cognitive impairment

作　　者：范佳旭 乔俊鹏 费海程 成芳 陈学禹 赵云 贾红英[3] Fan Jiaxu;Qiao Junpeng;Fei Haicheng;Cheng Fang;Chen Xueyu;Zhao Yun;Jia Hongying(Department of Biostatistics,School of Public Health,Shandong University,Jinan 250012,China;Licheng District Center for Disease Control and Prevention of Jinan,Jinan 250100,China;Dean′s Office,Second Hospital of Shandong University,Jinan 250033,China)

机构地区：[1]山东大学公共卫生学院生物统计学系,济南250012 [2]济南市历城区疾病预防控制中心,济南250100 [3]山东大学第二医院院长办公室,济南250033

出　　处：《中华老年多器官疾病杂志》2024年第10期793-796,共4页Chinese Journal of Multiple Organ Diseases in the Elderly

基　　金：中央引导地方科技发展资金自由探索类基础研究项目(2021Svup070);山东大学第二医院科研发展基金(6010220052)。

摘　　要：随着人口老龄化在全球范围内的加剧,由于衰老引起的阿尔茨海默病和其他相关痴呆等认知障碍问题愈发明显。这些问题不仅严重影响老年人的健康和生活质量,同时给社会带来沉重的负担。越来越多的研究发现,除了年龄、性别及各类慢性疾病等常见的危险因素外,血脂水平在识别认知功能障碍和预防痴呆过程中起着越来越重要的预测作用。本文通过对血脂水平与认知障碍相关性的文献进行综述,重点讨论血脂水平对认知功能的影响及其作用机制、传统和非传统血脂水平与认知障碍的关系,以期对认知障碍的临床诊断和防治提供新的思路和参考。As population ageing is intensifying globally,the problem of cognitive disorders such as Alzheimer′s disease and other related dementias due to ageing is becoming more pronounced.These problems not only seriously affect the health and quality of life of older people,but also bring a heavy burden to society.More and more studies have found that,in addition to common risk factors such as age,gender and various chronic diseases,lipid levels play an increasingly important predictive role in identifying cognitive dysfunction and preventing dementia.In this paper,we reviewed the literature on the correlation between blood lipid levels and cognitive impairment,and focused on the effect of lipid levels on cognitive impairment,their action mechanism,and the traditional and non-traditional relationship between them,with a view to providing new ideas and references for the clinical diagnosis and prevention of cognitive impairment.

关 键 词：认知障碍 血脂 相关性 

分 类 号：R589.2[医药卫生—内分泌] R749.16[医药卫生—内科学]