如何选择去肾神经术治疗高血压的最适宜人群  

How to Select the Optimal Population for Renal Denervation in the Treatment of Hypertension

作　　者：封欣妤 张冬颖[2] 邹玉宝[3] 冯颖青[4] 程康 FENG Xinyu;ZHANG Dongying;ZOU Yubao;FENG Yingqing;CHENG Kang(Department of Cardiology,Xi’an People’s Hospital(Xi’an Fourth Hospital),Xi’an 710199,Shaanxi,China;Department of Cardiology,The First Affiliated Hospital of Chongqing Medical University,Chongqing 400042,China;Department of Cardiology Ward 1,Fuwai Hospital,National Center for Cardiovascular Diseases,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100037,China;Department of Cardiology,Guangdong Provincial People’s Hospital,Guangzhou 510080,Guangdong,China)

机构地区：[1]西安市人民医院(西安市第四医院)心血管内科,陕西西安710199 [2]重庆医科大学附属第一医院心血管内科,重庆400042 [3]中国医学科学院北京协和医学院国家心血管病中心阜外医院心血管中心一病区,北京100037 [4]广东省人民医院心血管内科,广东广州510080

出　　处：《心血管病学进展》2024年第10期885-889,共5页Advances in Cardiovascular Diseases

摘　　要：去肾神经术(RDN)的研发经历了异常曲折的历程,虽然选择肾交感神经兴奋性高的高血压患者施行RDN有客观的理论基础,但是目前缺乏评价患者肾交感神经兴奋性与高血压关联程度的特异性筛选指标。同时既往研究入选的患者纷繁庞杂,报道的结果也不一致,带来了诸多困惑。现汇总国内外指南/共识/科学声明推荐RDN的适宜及建议排除人群,阐述目前推荐RDN适宜人群的筛选方法,期待更多的临床数据进一步明晰RDN的适应证,以提高降压疗效。The development of renal denervation(RDN)has experienced an unusually tortuous process.Although there are some objective theoretical basis for selecting hypertensive patients with high renal sympathetic nerve excitability for RDN surgery,there is no specific screening index to evaluate the correlation between renal sympathetic excitability and hypertension.At the same time,the patients enrolled in previous studies were numerous and varied,and the reported results were inconsistent,which brought us a lot of confusion.This paper summarized the suitable and excluded groups recommended by international guidelines/consensus/scientific statements for RDN,described the current screening methods for suitable groups recommended for RDN,and looked forward to getting more clinical data to clarify the indication of RDN and improve the antihypertensive efficacy.

关 键 词：高血压 去肾神经术 适应证 禁忌证 

分 类 号：R544.1[医药卫生—心血管疾病]