经皮去肾神经术治疗高血压的临床获益:证据和争议  

Clinical Benefit of Renal Denervation in the Treatment of Hypertension:Evidence and Controversy

作　　者：董一飞[1] 张毅[2] 李燕[3] 贾楠 DONG Yifei;ZHANG Yi;LI Yan;JIA Nan(Department of Cardiology,The Second Affiliated Hospital of Nanchang University,Nanchang 330008,Jiangxi,China;Department of Cardiology,The Tenth People’s Hospital Affiliated to Tongji University(Shanghai Tenth People’s Hospital),Shanghai 200072,China;Shanghai Institute of Hypertension,Ruijin Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200001,China;Minimally Invasive Interventional Treatment Center,Qingdao Municipal Hospital,Qingdao 266011,Shandong,China)

机构地区：[1]南昌大学第二附属医院心内科,江西南昌330008 [2]同济大学附属第十人民医院(上海市第十人民医院)心内科,上海200072 [3]上海市高血压研究所上海交通大学医学院附属瑞金医院,上海200001 [4]青岛市市立医院微创介入治疗中心,山东青岛266011

出　　处：《心血管病学进展》2024年第10期890-896,共7页Advances in Cardiovascular Diseases

基　　金：江西省科技厅应用研究培育(临床医学领域)(20212BAG70030)。

摘　　要：高血压是全球心血管疾病发病率和死亡率增加重要的可改变的危险因素之一。尽管目前有多种药物治疗和非药物治疗方法,高血压的控制率仍较低。经皮去肾神经术是一种微创介入手术,其作为一种新兴的高血压治疗方法备受关注,十余年来开展了一系列的临床研究。现总结当前经皮去肾神经术治疗高血压临床获益的证据和争议,旨在指导临床实践并推动相关研究的进展。Hypertension is a potent modifiable risk factor for global cardiovascular morbidity and mortality.Despite the availability of various pharmacological and non-pharmacological interventions,the control rate of hypertension remains low.Renal denervation(RDN)is a minimally invasive interventional procedure that has garnered significant attention as an emerging therapeutic modality,with a series of clinical studies conducted over the past decade.In this article,we summarize the evidence and controversy regarding the clinical benefits of RDN in treating hypertension,aiming to guide clinical practice and advance related research.

关 键 词：去肾神经术 高血压 交感神经系统 

分 类 号：R544.1[医药卫生—心血管疾病]