中药内治法治疗糖尿病肾病的研究进展  

Research progress in the treatment of diabetes nephropathy with internal treatment of traditional Chinese medicine

作　　者：汪四海[1,2,3,4] 方朝晖 李瑜璠[1,2,3] 经加吻 WANG Sihai;FANG Zhaohui;LI Yufan;JING Jiawen(The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine,Hefei 230031,CHN;Institute of TCM Prevention and Treatment of Diabetes,Anhui Academy of Chinese Medicine Sciences,Hefei 230031,CHN;Xin'an Institute of Medicine and Modernization of Traditional Chinese Medicine,One Health Institute of Comprehensive National Science Center,Hefei 230031,CHN;Key laboratory of Xin an Medical Science,Ministry of Education,Hefei 230038,CHN)

机构地区：[1]安徽中医药大学第一附属医院内分泌科,合肥230031 [2]安徽省中医药科学院中医药防治糖尿病研究所,合肥230031 [3]综合性国家科学中心大健康研究院新安医学与中医药现代化研究所,合肥230031 [4]新安医学教育部重点实验室,合肥230038

出　　处：《河南大学学报（医学版）》2024年第5期313-317,340,共6页Journal of Henan University:Medical Science

基　　金：国家自然科学基金(82174153);安徽省卫健委青年基金(AHWJ2023A30274);安徽省高校自然科学研究重点项目(2022AH050488);2022年新安医学教育部重点实验室开放课题重点项目(2022xayx05);2020年安徽中医药大学自然科学研究重点项目(2020yfyzc24);2021年安徽中医药大学教学研究重点项目(2021xjjy_zd036)。

摘　　要：糖尿病肾病(diabetic nephropathy,DN)是糖尿病(diabetes mellitus,DM)患者严重的微血管并发症,若不及时救治、采取有效措施,很快就发展到慢性肾功能衰竭。因此,对于DN患者,尽早及时有效地干预十分必要。西医治疗DN不外乎降糖、降压、调脂、改善循环等综合处理,长期服用患者依从性差、副作用多,远期疗效有待进一步考证。中医药具有整体调节、辨证论治的独特优势,在改善症状、提高生活质量等方面具有显著疗效。本文从中药复方、中成药、中药单体或提取物内服三个方面治疗DN作一综述,以期找出中药内治法治疗DN的规律,发现其优势,找出其不足,为后期中药内服法治疗DN提供参考。Diabetes nephropathy(DN)is a serious microvascular complication of diabetes patients.If we do not take timely treatment and effective measures,it will soon develop to chronic renal failure.Therefore,for DN patients,it is necessary to intervene as soon as possible,in a timely and effective manner.The treatment of DN with Western medicine involves comprehensive treatments such as lowering blood sugar,lowering blood pressure,regulating blood lipids,and improving circulation.Patients who take it for a long time have poor compliance and many side effects,and the long-term efficacy needs further investigation.Traditional Chinese medicine has unique advantages in overall regulation and syndrome differentiation and treatment,and may have significant therapeutic effects in improving symptoms and improving quality of life.This article reviews the treatment of DN from three aspects:compound Chinese medicine,traditional Chinese patent medicines and simple preparations,and oral administration of Chinese medicine monomer or extract,in order to find out the rule of internal treatment of DN with Chinese medicine,point out its advantages and disadvantages,and provide reference value for the later treatment of DN with internal administration of Chinese medicine.

关 键 词：中药 内治法 糖尿病肾病 研究进展 

分 类 号：R587.1[医药卫生—内分泌]