生殖道支原体感染与不孕不育、妇科疾病的相关性  

Study on the correlation between mycoplasma infection of reproductive tract and infertility and gynecological diseases

作　　者：林晓红 陈志浩 李佳 杨红 陈柳 LIN Xiaohong;CHEN Zhihao;LI Jia;YANG Hong;CHEN Liu(The First Affiliated Hospital of Chinese People's Liberation Army Air Force Medical University,Xian,710032,CHN)

机构地区：[1]中国人民解放军空军军医大学第一附属医院妇产科,西安710032

出　　处：《河南大学学报（医学版）》2024年第5期361-364,共4页Journal of Henan University:Medical Science

基　　金：国家自然科学基金面上项目(82172993)。

摘　　要：目的:分析门诊女性患者支原体感染情况以及与不孕不育、妇科疾病的相关性。方法:回顾性分析6943例门诊女性患者的支原体感染情况,并分析临床诊断为HPV感染、阴道炎及不孕、不良孕史等患者的支原体感染相关性。结果:共检测6943例女性泌尿生殖道样本,支原体阳性2507例,总阳性率为36.1%,≤20岁女性的阳性率高达56.0%。其中微小脲原体3型阳性率最高达12.5%,解脲脲原体阳性率为8.4%,人型支原体和生殖支原体的阳性率分别是7.9%和0.4%;不孕组、HPV感染组和阴道炎组的阳性率分别为44.8%、44.7%和42.9%,与对照组相比χ^(2)值分别为15.871、12.500、25.337,P<0.001,与正常组相比具有显著差异。结论:支原体感染在不同年龄段分布不同,且与不孕、HPV感染和阴道炎相关,临床应加强支原体筛查,早诊断、早治疗。Objective:To analyze mycoplasma infection in outpatient female patients and its correlation with infertility and gynecological diseases.Methods:6943 outpatients and the association of mycoplasma infection in patients diagnosed with HPV infection,vaginitis and infertility and adverse pregnancy history.Results:A total of 6943 female urogenital tract samples were tested,2512 cases,The overall positive rate was 36.1%,The positive rate of women aged 20 years was as high as 56.0%;Among them,the highest positive rate of ureaplasma type 3:12.5%,The positive rate of ureaplasma species was 8.4%,The positive rates of M.hominis and M.genitalium were 7.9%and 0.4%,respectively;The positive rates of infertility group,HPV infection group and vaginitis group were:44.8%,44.7%and 42.9%,respectively,Theχ^(2) values were 15.871,12.500,and 25.337,respectively,P<0.001,Significant different compared to the normal group.Conclusion:The distribution of mycoplasma infection in different ages,and is associated with infertility,HPV infection and vaginitis,clinical should strengthen mycoplasma screening,early diagnosis and early treatment.

关 键 词：生殖道支原体感染 解脲脲原体 微小脲原体 人型支原体 生殖支原体 

分 类 号：R375[医药卫生—病原生物学]