基于各种感觉性刺激因素对慢性意识障碍患者促醒效果的比较研究  

A comparative study on the wakefulness promoting effect of various sensory stimuli on patients with chronic consciousness disorders

作　　者：刘全丰 刘世文 陈奎 严燕芬 阚绍龙 Liu Quanfeng;Liu Shiwen;Chen Kui;Yan Yanfen;Kan Shaolong(Shenzhen Hengsheng Hospital,Shenzhen,Guangdong 518102,China)

机构地区：[1]深圳恒生医院,广东深圳518102

出　　处：《首都食品与医药》2024年第20期57-59,共3页Capital Food Medicine

基　　金：深圳市宝安区医疗卫生科研项目(2022JD054)。

摘　　要：目的探究各种感觉性刺激因素对慢性意识障碍(PDOC)患者促醒效果.方法选取2023年1月-2024年6月期间在深圳恒生医院接受康复训练的60例PDOC患者进行研究,按照随机数字表法分为对照组(n=30,常规养护管理)与观察组(n=30,基于各种感觉性刺激因素的促醒训练),观察患者治疗前后的昏迷恢复量表修改版(CRS-R)、格拉斯哥昏迷量表(GOS-E)评分以及脑电图Synek分级,并记录治疗后并发症的发生情况.结果治疗前所有患者CRS-R、GOS-E评分无明显差异,P>0.05,治疗后,观察组行为状态评分高于对照组,P<0.05;观察组患者脑电图Synek分级优于对照组,P<0.05;观察组并发症发生率为3.33%,显著低于对照组的26.67%,P<0.05.结论对于PDOC患者采用基于各种感觉性刺激因素的促醒训练临床效果更好,能够有效改善患者的昏迷状态,且该刺激方法安全性较高,不良反应发生风险较低,值得临床应用推广.Objective To explore the effects of various sensory stimuli on awakening in patients with chronic consciousness disorder(PDOC).Methods A study was conducted on 60 PDOC patients who received rehabilitation training at Shenzhen Hang Seng Hospital from January 2023 to June 2024.They were randomly divided into a control group(n=30,routine care management)and an observation group(n=30,awakening training based on various sensory stimuli)using a random number table method.The modified version of the Coma Recovery Scale(CRS-R),Glasgow Coma Scale(GOS-E)scores,and EEG Synek grading were observed before and after treatment,and the incidence of complications after treatment was recorded.Results Before treatment,all patients CRS-R and GOS-E scores there is no difference,P>0.05,after treatment,the behavioral status score of the observation group was higher than that of the control group,P<0.05;the Synek grading of EEG in the observation group was better than that in the control group,P<0.05;the incidence of complications in the observation group was 3.33%,significantly lower than that in the control group at 26.67%,P<0.05.Conclusion The use of awakening training based on various sensory stimuli has better clinical effects on PDOC patients,can effectively improve their coma state,and this stimulation method is safer with lower risk of adverse reactions.It is worthy of clinical application and promotion.

关 键 词：各种感觉性刺激因素 慢性意识障碍 促醒效果 脑电图 

分 类 号：R49[医药卫生—康复医学]