功能化纳米复合材料在生物传感器中的应用进展  

Application progress of functionalized nanocomposites in biosensors

作　　者：刘思敏 陈华 潘洪志 Liu Simin;Chen Hua;Pan Hongzhi(School of Health Science and Engineering,University of Shanghai for Science and Technology,Shanghai 200093,China;Collaborative Research Center,Shanghai University of Medicine and Health Sciences,Shanghai 201318,China)

机构地区：[1]上海理工大学健康科学与工程学院,上海200093 [2]上海健康医学院协同科研中心,上海201318

出　　处：《国际生物医学工程杂志》2024年第4期382-387,共6页International Journal of Biomedical Engineering

基　　金：国家自然科学基金(82273687, 81973097)。

摘　　要：功能化纳米材料结合并固定识别元件构建生物传感界面是生物传感器检测的核心环节。新型纳米材料如金属有机框架材料(MOFs)、层状双氢氧化物材料(LDHs)、贵金属类纳米材料、磁性材料、共价有机框架材料(COFs)、碳族材料及其他材料如导电聚合物等, 利用不同性能、结构和形态的功能化纳米材料进行界面修饰, 已经研制出多种性能优异的生物传感器, 拓展了应用范围。主要综述了功能化纳米复合材料的种类及其构建的生物传感器的应用进展。Functionalized nanomaterials combined and immobilized with recognition elements to construct biosensing interfaces are the core aspects of biosensor detection.By interfacially modifying functionalized nanomaterials with different properties,structures and morphologies,the application scope of nanomaterials can be expanded,such as metal-organic frameworks(MOFs),layered double hydroxides(LDHs),noble metal particles,magnetic materials,covalent organic frameworks(COFs),carbon-group materials,and conductive polymers.Based on these novel nanomaterials,a variety of biosensors with excellent performance have been developed.In this review paper,the types of functionalized nanocomposites and their progress in the application of constructed biosensors were summerized.

关 键 词：生物传感器 金属有机框架材料 层状双氢氧化物材料 贵金属类纳米材料 磁性材料 共价有机框架材料 碳族材料 

分 类 号：R318.08[医药卫生—生物医学工程]