Ag(I)-Catalyzed Addition of Cyclopropenones and Alcohols via C—C Bond Cleavage  

银催化环丙烯酮与醇的C-C键断裂加成反应

作　　者：Zhang Shulin Zhang Zhou Sun Meng 张书林;张周;孙萌(西北大学化学与材料科学学院、合成与天然功能分子教育部重点实验室,西安710127)

机构地区：[1]Key Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education,College of Chemistry and Materials Science,Northwest University,Xi'an 710127

出　　处：《有机化学》2024年第7期2233-2240,共8页Chinese Journal of Organic Chemistry

基　　金：Project supported by the National Natural Science Foundation of China(No.21702160);the State Key Laboratory of Fine Chemicals,Dalian University of Technology(No.KF2311)。

摘　　要：An efficient method for the synthesis of α-phenylcinnamates via silver catalyzed C—C bond activation reaction of cyclopropenone and alcohol was developed.This protocol features a simple reaction system,specific regioselectivity,good functional group compatibility and good yields.It is of great significance for the later modification of natural products.发展了一种银催化的环丙烯酮与醇的C-C键活化反应合成α-苯基肉桂酸酯的高效方法.该反应条件温和,区域选择性专一,底物官能团兼容性好,产物收率高,对于天然产物的后期修饰具有重要意义.

关 键 词：silver catalysis C—C bond activation cyclopropenone nucleophilic addition 

分 类 号：O621.251[理学—有机化学]