尿常规检验中常用4项指标在老年高血压诊断中的应用价值  

Application Value of 4 Indexes Commonly Used in Urine Routine Examination in the Diagnosis of Hypertension in the Elderly

作　　者：郑宇 刘思雨 Zheng Yu;Liu Siyu(Department of Clinical Laboratory,Beijing Chaoyang District Anzhen Community Health Service Center,Beijing 100011,China)

机构地区：[1]北京市朝阳区安贞社区卫生服务中心检验科,北京100011

出　　处：《中国社区医师》2024年第29期81-83,共3页Chinese Community Doctors

摘　　要：目的:探讨尿常规检验中常用4项指标在老年高血压诊断中的应用价值。方法:选取2022年1月—2023年12月北京市朝阳区安贞社区卫生服务中心诊治的120例老年高血压患者作为试验组,选取同期60例健康体检者作为对照组,均行尿常规检验[24 h尿蛋白定量(24 hUTP)、尿微量白蛋白(mAlb)、尿β_2微球蛋白(β_2-MG)、N-乙酰-β-D氨基葡萄糖苷酶(NAG)],比较试验组与对照组、不同高血压分级患者(轻度组、中度组、重度组)、不同高血压病程患者尿常规指标水平。结果:试验组24 hUTP、mAlb、β_2-MG、NAG水平高于对照组(P<0.05)。不同高血压分级患者24 hUTP、mAlb、β_2-MG、NAG水平对比,重度组>中度组>轻度组,有统计学差异(P<0.05)。不同高血压病程患者尿常规指标水平对比,高血压病程>20年患者24 hUTP、mAlb、β_2-MG、NAG水平最高,其次分别为0~10年患者、>10~20年患者,有统计学差异(P<0.05)。结论:尿常规检验中常用4项指标在老年高血压诊断中的应用价值较高,其水平与高血压分级、病程密切相关,可为治疗方案的制定提供依据。Objective:To explore the application value of 4 indexes commonly used in routine urine test in the diagnosis of hypertension in the elderly.Methods:A total of one hundred and twenty elderly hypertensive patients diagnosed and treated in Beijing Chaoyang District Anzhen Community Health Service Center from January 2022 to December 2023 were selected as the experimental group.Sixty healthy subjects were selected as control group.All patients underwent routine urine tests[24 h urinary protein quantity(24 hUTP),urinary microalbumin(mAlb),urinaryβ2 microglobulin(β2-mg),n-acetyl-β-D glucosaminidase(NAG)].Urine routine indexes of experimental group and control group,patients with different hypertension grades(mild group,moderate group,severe group)and patients with different hypertension course were compared.Results:The levels of 24 hUTP,mAlb,β2-MG and NAG in experimental group were higher than those in control group(P<0.05);the levels of 24 hUTP,mAlb,β2-MG and NAG in patients with different hypertension grades were compared,severe group>moderate group>mild group,the difference was statistically significant(P<0.05);comparison of urinary routine indicators in patients with different stages of hypertension shows that patients with hypertension for more than 20 years have the highest levels of 24-hour UTP,mAlb,β2-MG,and NAG,the patients with 0~10 years and>10~20 years were followed by patients,the difference was statistically significant(P<0.05).Conclusion:The four indexes commonly used in routine urine examination have high application value in the diagnosis of hypertension in the elderly,and their levels are closely related to the grade and course of hypertension,which can provide a basis for the formulation of treatment plan.

关 键 词：老年 高血压 尿常规检验 

分 类 号：R544[医药卫生—心血管疾病]