IgA肾病中西医指标相关性分析  

Correlation Analysis on TCM and Western Medicine Indexes in lgA Nephropathy

作　　者：郝梦 刘涛[2] 徐静雯 孙函 朱彦[1] HAO Meng;LIU Tao;XU Jingwen;SUN Han;ZHU Yan(Institute of Information on Traditional Chinese Medicine,China Academy of Chinese Medical Sciences,Beijing 100700,China;Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing 100091,China;School of Pharmaceutical Information,Changchun University of Traditional Chinese Medicine,Changchun 130117,China)

机构地区：[1]中国中医科学院中医药信息研究所,北京100700 [2]中国中医科学院西苑医院,北京100091 [3]长春中医药大学医药信息学院,长春130117

出　　处：《中国中医药图书情报杂志》2024年第6期136-140,共5页Chinese Journal of Library and Information Science for Traditional Chinese Medicine

基　　金：中国中医科学院科技创新工程(CI2021A01211);国家自然科学基金面上项目(82174534)。

摘　　要：目的探讨IgA肾病(IgAN)基本情况、分级情况、中医指标、西医指标的相关性。方法以患者编号为桥梁,运用Access查询整理数据,收集IgAN患者基本情况、分级情况、中医指标、西医指标等信息,选取条目22项。利用ChiPlot软件将所有条目进行Spearman相关性分析。采用典型相关分析探讨IgAN患者基本情况、分级情况、中医指标、西医指标的整体相关性。结果共纳入患者92例,在Spearman相关性分析中,除腰痛指标外,基本情况、分级情况、中医指标、西医指标中,各变量与一个或几个变量具有一对一相关性关系。在典型相关性分析中,WX、WZ、XZ、YZ等4对变量P<0.05且典型相关系数>0,分别呈正相关。结论基本情况与分级情况、基本情况与西医指标,分级情况与西医指标、中医指标与西医指标分别具有典型相关性。将中医指标、西医指标、分级情况与基本情况相结合,可为全面客观辨证及中西医结合诊疗提供一定参考。Objective To explore the correlation between the basic situation,grading,TCM indicators,and Western medicine indicators of IgA nephropathy(IgAN).Methods Using the total number of patients as a bridge,Access was used to query and collate the data.The information of TCM indexes,Western medicine indexes,grading situation and basic situation of patients with IgAN was collected.22 items were selected.Spearman correlation analysis was performed on all items using ChiPlot software.Canonical correlation analysis was used to investigate the overall correlation of TCM indexes,Western medicine indexes,grading and basic conditions in IgAN patients.Results A total of 92 patients were included.In Spearman correlation analysis,except for the index of low back pain,each variable had one-to-one correlation with one or several variables in basic situation,grading situation,TCM indexes and Western medicine indexes.In the canonical correlation analysis,WX,WZ,XZ and YZ were positively correlated with P<0.05 and canonical correlation coefficient>0,respectively.Conclusion There are typical correlations between basic condition and grading condition,basic condition and Western medicine indexes,grading condition and Western medicine indexes,and TCM indexes and Western medicine indexes respectively.Based on the whole,combining TCM indexes,Western indexes,grading and basic conditions can provide a certain reference for comprehensive and objective syndrome differentiation and integrated diagnosis and treatment of traditional Chinese and Western medicine.

关 键 词：IGA肾病 中医主证 理化指标 典型相关性分析 

分 类 号：R256.5[医药卫生—中医内科学]