靳三针疗法治疗失眠Meta分析  

Meta-analysis on Jin’s Three-needle Therapy for the Treatment of Insomnia

作　　者：张晚霞 陈龙 唐纯志 ZHANG Wanxia;CHEN Long;TANG Chunzhi(Clinical School of Acupuncture Rehabilitation,Guangzhou University of Chinese Medicine,Guangzhou 510006,China;The Fifth Clinical College,Guangzhou University of Chinese Medicine,Guangzhou 510095,China)

机构地区：[1]广州中医药大学针灸康复临床医学院,广东广州510006 [2]广州中医药大学第五临床医学院,广东广州510095

出　　处：《中国中医药图书情报杂志》2024年第6期238-245,共8页Chinese Journal of Library and Information Science for Traditional Chinese Medicine

摘　　要：目的基于Meta分析评估靳三针疗法治疗失眠症的临床疗效。方法检索PubMed、Embase、Web of Science(WOS)核心合集、Cochrane Library、中国知识资源总库(CNKI)、中文科技期刊数据库(VIP)、中国学术期刊数据库(万方数据)、中国生物医学文献数据库(CBM),收集建库至2023年6月1日靳三针治疗失眠的随机对照试验(RCT),使用RevMan5.4软件和Stata16.0软件进行Meta分析。结果共纳入23篇RCTs,总样本量1884例。其中21项研究报告了临床有效率,21项研究报告了匹兹堡睡眠质量指数评分(PSQI),5项研究报告了中医证候积分,3项研究报告了复发率,4项研究报告了不良事件发生率。Meta分析显示,靳三针疗法治疗失眠的临床有效率[MD=2.74,95%CI(1.81,4.71),P<0.00001]优于对照组;试验组PSQI评分[MD=-3.49,95%CI(-4.73,-2.25),P<0.00001]、中医证候积分[MD=-3.49,95%CI(-3.67,-3.31),P<0.00001]、复发率[MD=0.33,95%CI(0.16,0.68),P=0.002]、不良事件发生率[MD=0.38,95%CI(0.18,0.78),P=0.009]均低于对照组。靳三针联合其他疗法的临床有效率[MD=3.76,95%CI(2.31,6.10),P<0.00001]高于对照组,PSQI评分[MD=-3.32,95%CI(-4.78,-1.86),P<0.00001]低于对照组。漏斗图大致对称,Begg’s检验P=0.174>0.05,表明结果基本可靠,不存在发表偏倚。敏感性分析结果显示,未发现有明显逆转Meta分析结果的研究,表明纳入研究的结果较可靠。结论靳三针疗法治疗失眠临床有效率显著提升,PSQI评分和中医证候积分有所降低,但仍需更多大样本、高质量的RCT加以验证。Objective To evaluate the efficacy of Jin’s three-needle therapy for the treatment of insomnia based on Meta-analysis.Methods Cochrance Library,Embase,Web of science,Pubmed,CBM,Wanfang Data,CNKI,VIP were retrieved.The RCTs of Jin’s three-needle therapy in treating insomnia in the above 7 databases were collected since the establishment of the databases to June 1,2023.RevMan 5.4 software and Stata 16.0 software were used to perform Meta-analysis on the included studies.Results A total of 23 RCTs were included,with a total sample size of 1884.Of these RCTs,21 reported clinical effective rate,21 reported Pittsburgh Sleep Quality Index scores(PSQI),5 reported TCM syndrome scores,3 reported recurrence rate,and 4 reported adverse event rate.Meta-analysis showed that the clinical effective rate of Jin’s three-needle therapy in treating insomnia[MD=2.74,95%CI(1.81,4.71),P<0.00001]was better than that of the control group;PSQI scores[MD=-3.49,95%CI(-4.73,-2.25),P<0.00001],TCM syndrome scores[MD=-3.49,95%CI(-3.67,-3.31),P<0.00001],recurrence rate[MD=0.33,95%CI(0.16,0.68),P=0.002],adverse event rate[MD=0.38,95%CI(0.18,0.78),P=0.009]were lower than those in the control group;the clinical effective rate of Jin’s three-needle therapy combined with other therapies[MD=3.76,95%CI(2.31,6.10),P<0.00001]was higher than that of the control group,and PSQI scores(PSQI)[MD=-3.32,95%CI(-4.78,-1.86),P<0.00001]were lower than that of the control group.The funnel plot was roughly symmetrical,and Begg’s test P=0.174>0.05 indicated that the results were basically reliable and there was no publication bias.The results of sensitivity analysis showed that no studies significantly reversed the results of meta-analysis,indicating that the results of included studies were reliable.Conclusion The clinical efficacy of Jin’s three-needle therapy in treating insomnia has significantly improved,with a decrease in PSQI score and TCM syndrome scores.However,more large-scale and high-quality randomized controlled trials are still needed for ver

关 键 词：针刺疗法 靳三针 失眠 随机对照试验 系统评价 META分析 

分 类 号：R256.23[医药卫生—中医内科学]