肠道菌群与妊娠糖尿病关系的进展分析  

Progress Analysis of the Relationship between Intestinal Flora and Gestational Diabetes Mellitus

作　　者：季静霞 Ji Jingxia(Department of Obstetrics,Cangzhou Qingxian People's Hospital,Cangzhou 062650,Hebei Province,China)

机构地区：[1]沧州市青县人民医院产科,河北沧州062650

出　　处：《中外医药研究》2024年第25期166-168,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

摘　　要：妊娠糖尿病的发生与肠道菌群的变化密切相关。该综述系统总结和分析了近年来关于肠道菌群与妊娠糖尿病关系的研究进展,为妊娠糖尿病的预防和治疗提供了新的思路。妊娠糖尿病孕妇肠道菌群的α多样性显著降低,表现为有益菌减少和致病菌增加,β多样性也显示出显著的个体差异。这些变化可能与激素水平变化、肠道屏障功能受损、饮食结构不良、炎性反应增强以及免疫系统变化等机制有关。The occurrence of gestational diabetes mellitus is closely related to the changes of intestinal flora.This review systematically summarized and analyzed the research progress on the relationship between intestinal flora and gestational diabetes in recent years,and provided a new idea for the prevention and treatment of gestational diabetes.Theαdiversity of intestinal flora in pregnant women with gestational diabetes was significantly decreased,which showed a decrease of beneficial bacteria and an increase of pathogenic bacteria,and theβdiversity also showed significant individual differences.These changes may be related to changes in hormone levels,impaired intestinal barrier function,poor diet,enhanced inflammatory response,and changes in the immune system.

关 键 词：肠道菌群 妊娠糖尿病 Α多样性 Β多样性 

分 类 号：R714.256[医药卫生—妇产科学]