工作场所中有毒氯化物的碱液吸收-离子色谱测定法  

Alkali absorption ion chromatography method for the determination of toxic chloride substances in the workplace

作　　者：时燕 臧旭芳 时燕华 SHI Yan;ZANG Xufang;SHI Yanhua(Guiyang Nanming District Center for Disease Control and Prevention,Guiyang,Guizhou 550002,China;Experimental Testing Brigade,Jiangxi Bureau of Geology,Nanchang,Jiangxi 330001,China)

机构地区：[1]贵阳市南明区疾病预防控制中心,贵州贵阳550002 [2]江西省地质局实验测试大队,江西南昌330001

出　　处：《职业与健康》2024年第14期1911-1914,共4页Occupation and Health

摘　　要：目的探索快速、准确检测工作场所空气中有毒氯化物的方法,降低有毒氯化物对实验人员的危害。方法使用3.3 mmol/L碳酸钠和3.0 mmol/L碳酸氢钠混合碱性液吸收工作场所中的氯,以改进GBZ/T 160.37—2004《工作场所空气有毒物质测定氯化物》中大型气泡吸收管采集方法,并用离子色谱法代替甲基橙分光光度法进行测定,以无机化学实验室场所空气为样品,进行2种方法对比验证。结果改进后的离子色谱法检出限为0.05 mg/L,最低检出浓度为0.05 mg/m^(3),优于GBZ/T 160.37—2004《工作场所空气有毒物质测定氯化物》中0.2 mg/L的检出限和0.2 mg/m^(3)的最低检出浓度。采集2个工作场所环境空气实际样品进行6次重复测定验证其精密度,测得相对标准偏差分别为0.62%和2.33%,符合GBZ/T 160.37—2004《工作场所空气有毒物质测定氯化物》中甲基橙分光光度法中相对标准偏差的范围要求(0.7%~2.8%)。测定4类氯化物质控样与甲基橙分光光度法进行准确度实验,平均值与质控标样认定值的相对误差范围分别为-1.48%~3.43%和-2.35%~2.88%。结论离子色谱法检测氯化物的灵敏度高,可提高自动化分析效率,满足工作场所中有毒物质氯化物的测定要求。Objective To explore a rapid and accurate method to detect toxic chloride in the workplace and reduce the harm of toxic chloride to laboratory personnel.Methods The mixed alkaline solution of 3.3 mmol/L sodium carbonate and 3.0 mmol/L sodium bicarbonate was used to absorb chlorine in the workplace,to improve the large bubble absorption tube collection method in GBZ/T 160.37-2004"determination of chloride in the air of workplaces",and the ion chromatography method was used to replace the methyl orange spectrophotometric method for determination,and the air in the inorganic chemistry laboratory was used as the sample for comparison and verification of the two methods.Results The detection limit of the improved ion chromatography method was 0.05 mg/L,and the minimum detection concentration was 0.05 mg/m^(3),which was better than the detection limit of 0.2 mg/L and the minimum detection concentration of 0.2 mg/m^(3)in GBZ/T 160.37-2004"determination of chloride in the air of workplaces".The environmental air samples from two workplaces were collected for six repeated determinations to verify the precision,and the relative standard deviations were 0.62%and 2.33%,respectively,which met the range requirements(0.7%-2.8%)of the relative standard deviation in the methyl orange spectrophotometric method in GBZ/T 160.37-2004"determination of chloride in the air of workplaces".The accuracy comparison experiment between the control sample of four kinds of chlorinated substances and methyl orange spectrophotometry was carried out.The relative error range between the average value and the certified value of quality control standard sample was-1.48%-3.43%and-2.35%-2.88%,respectively.Conclusion Ion chromatography has high sensitivity in the detection of chloride,which can improve the efficiency of automated analysis and meet the requirements for the determination of toxic substances in the workplace.

关 键 词：离子色谱法 分光光度法 工作场所 氯化物 

分 类 号：R115[医药卫生—公共卫生与预防医学]