强力定眩片联合倍他司汀治疗良性阵发性位置性眩晕的效果及对脑部血流状态的影响  

Effect of Qiangli Dingxuan tablets combined with betahistine in the treatment of benign paroxysmal positional vertigo and its influence on cerebral blood flow state

作　　者：王文哲 成龙 李海荣 WANG Wenzhe;CHENG Long;LI Hairong(Encephalopathy Emergency Department,Xianyang Hospital of Yan'an University,Xianyang 712000,China;Neurology Department,Xianyang Hospital of Yan'an University,Xianyang 712000,China)

机构地区：[1]延安大学咸阳医院脑病急诊科,陕西咸阳712000 [2]延安大学咸阳医院神经内科,陕西咸阳712000

出　　处：《临床医学研究与实践》2024年第30期21-24,共4页Clinical Research and Practice

摘　　要：目的探讨强力定眩片联合倍他司汀治疗良性阵发性位置性眩晕的效果及对脑部血流状态的影响。方法选取2020年3月至2022年12月我院收治的80例良性阵发性位置性眩晕患者作为研究对象,根据随机数字表法将其分为对照组与观察组,各40例。对照组给予倍他司汀治疗,观察组在对照组基础上给予强力定眩片治疗。比较两组的治疗效果。结果观察组的治疗总有效率为95.00%,高于对照组的77.50%,差异具有统计学意义(P<0.05)。治疗前,两组大脑中动脉(MCA)、大脑前动脉(ACA)、大脑后动脉(PCA)的血流速度比较,差异无统计学意义(P>0.05);治疗后,观察组MCA、ACA、PCA的血流速度大于对照组,差异具有统计学意义(P<0.05)。治疗前,两组的前庭症状指数(VSI)、头晕残障问卷(DHI)评分比较,差异无统计学意义(P>0.05);治疗后,观察组的VSI、DHI评分均低于对照组,差异具有统计学意义(P<0.05)。结论强力定眩片联合倍他司汀治疗良性阵发性位置性眩晕患者不仅能够提升治疗效果,还能改善脑部血流状态、临床症状及生活质量,值得在临床中广泛应用推广。Objective To investigate the effect of Qiangli Dingxuan tablets combined with betahistine in the treatment of benign paroxysmal positional vertigo and its influence on cerebral blood flow state.Methods A total of 80 patients with benign paroxysmal positional vertigo admitted in our hospital from March 2020 to December 2022 were selected as the research objects and divided into control group and observation group by random number table method,with 40 cases in each group.The control group was treated with betahistine,and the observation group was treated with Qiangli Dingxuan tablets on the basis of the control group.The therapeutic effects of the two groups were compared.Results The total effective rate of treatment in the observation group was 95.00%,which was higher than 77.50%in the control group,and the difference was statistically significant(P<0.05).Before treatment,there were no significant differences in blood flow velocities of middle cerebral artery(MCA),anterior cerebral artery(ACA)and posterior cerebral artery(PCA)between the two groups(P>0.05);after treatment,the blood flow velocities of MCA,ACA and PCA in the observation group were larger than those in the control group,and the differences were statistically significant(P<0.05).Before treatment,there were no significant differences in Vestibular Symptom Index(VSI)and Dizziness Handicap Inventory(DHI)scores between the two groups(P>0.05);after treatment,the scores of VSI and DHI in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).Conclusion Qiangli Dingxuan tablets combined with betahistine in the treatment of patients with benign paroxysmal positional vertigo can not only enhance the therapeutic effect,but also improve the blood flow state of the brain,clinical symptoms and quality of life,which is worthy of wide application and promotion in clinical practice.

关 键 词：强力定眩片 倍他司汀 良性阵发性位置性眩晕 脑部血流状态 

分 类 号：R764[医药卫生—耳鼻咽喉科]