预防用抗菌药物专项管理对Ⅰ类手术切口预防性使用抗菌药物合理性的影响  

Effect of special management of prophylactic antibiotics on the rationality of prophylactic use of antibiotics in typeⅠsurgical incisions

作　　者：李阳 苏婉婷 王景景 LI Yang;SU Wanting;WANG Jingjing(Northwest Women's and Children's Hospital,Xi'an 710061;No.215 Hospital of Shaanxi Nuclear Industry,Xianyang 712000,China)

机构地区：[1]西北妇女儿童医院,陕西西安710061 [2]陕西省核工业二一五医院,陕西咸阳712000

出　　处：《临床医学研究与实践》2024年第30期174-177,共4页Clinical Research and Practice

基　　金：陕西省核工业二一五医院2020年院级科研立项项目(No.215KYJJ-202017)。

摘　　要：目的探究预防用抗菌药物专项管理对Ⅰ类手术切口预防性使用抗菌药物合理性的影响。方法选择2021年3月至2023年4月收治的248例Ⅰ类手术患者为研究对象,根据入院时间将其分为对照组、观察组,每组124例。对照组接受常规抗菌药物管理,观察组采取预防用抗菌药物专项管理。比较两组的管理效果。结果观察组的抗菌药物使用率低于对照组,差异具有统计学意义(P<0.05);观察组的抗菌药物使用时间短于对照组,差异具有统计学意义(P<0.05)。观察组的给药剂量不合理、用药疗程不合理、药物选择不合理、给药时机不合理及联合用药不合理发生率低于对照组,差异具有统计学意义(P<0.05)。观察组的不良反应总发生率低于对照组,差异具有统计学意义(P<0.05)。管理后,观察组的生理、心理精神、环境及社会文化评分高于对照组,差异具有统计学意义(P<0.05)。结论预防用抗菌药物专项管理用于Ⅰ类手术患者切口预防性使用抗菌药物管理中,可提高抗菌药物使用合理性,降低抗菌药物使用率及不良反应发生率,提高临床舒适度。Objective To explore the effect of special management of prophylactic antibiotics on the rationality of prophylactic use of antibiotics in typeⅠsurgical incisions.Methods A total of 248 patients with typeⅠsurgery admitted from March 2021 to April 2023 were selected as the research objects.According to the time of admission,the patients were divided into control group and observation group,with 124 cases in each group.The control group received routine antibacterial drug management,and the observation group received special management of prophylactic antibiotics.The management effects of the two groups were compared.Results The utilization rate of antibiotics in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05);the use time of antibiotics in the observation group was shorter than that in the control group,and the difference was statistically significant(P<0.05).The incidences of unreasonable dosage,unreasonable course of treatment,unreasonable drug selection,unreasonable timing of administration and unreasonable combination of drugs in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).The total incidence of adverse reactions in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).After management,the scores of physiology,psychology,environment and social culture in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).Conclusion The special management of prophylactic antibiotics used in the management of prophylactic use of antibiotics in patients with typeⅠsurgery can improve the rationality of the use of antibiotics,reduce the use rate of antibiotics and the incidence of adverse reactions,and improve clinical comfort.

关 键 词：预防用抗菌药物专项管理 Ⅰ类手术 预防性使用 舒适度 

分 类 号：R95[医药卫生—药学]