甘油三酯葡萄糖指数与青年冠状动脉慢血流现象的相关性研究  

Correlation between triglyceride-glucose index and coronary slow flow in young patients

作　　者：韦伟 贾宁[1] 佟海锋 杜大勇[2] 李沫言[2] 李巍[2] 刘畅[1] Wei Wei;Jia Ning;Tong Haifeng;Du Dayong;Li Moyan;Li Wei;Liu Chang(Department of Comprehensive Internal Medicine(Department of General Medicine),East Beijing Medical Branch,Chinese PLA General Hospital,Beijing 101149,China;不详)

机构地区：[1]解放军总医院京东医疗区综合内科(全科医学科),北京101149 [2]中国人民解放军第三○五医院心脏中心,北京100017

出　　处：《中国循证心血管医学杂志》2024年第9期1116-1118,共3页Chinese Journal of Evidence-Based Cardiovascular Medicine

摘　　要：目的探讨甘油三酯葡萄糖(TyG)指数与青年冠状动脉慢血流(CSF)现象的相关性。方法连续性选取2017年1月至2019年1月于中国人民解放军第三○五医院心内科住院经冠状动脉造影(CAG)诊断为CSF的青年(18岁≤年龄≤44岁)患者86例作为观察者(CSF组),在同时段内无冠状动脉器质性狭窄且冠状动脉血流速度正常的青年患者中参照随机数字表选取84例为对照组(NCSF组)。收集两组患者的临床资料、既往史、实验室检验数据、CAG结果,计算TyG指数,进行组间对比分析。用多因素Logistic回归分析确定青年CSF发生的危险因素,Pearson方法分析校正的心肌梗死榕栓试验帧数(CTFC)与TyG指数的相关性。结果CSF组患者体质指数、高血压病比例、总胆固醇、TyG指数高于NCSF组,差异有统计学意义(P<0.05)。多因素Logistic回归分析表明TyG指数(OR=1.984,95%CI:1.044~3.012,P<0.05)是青年CSF发生的独立危险因素。Pearson相关分析提示平均CTFC帧数与TyG指数水平呈正相关(r=0.496,P<0.05)。结论TyG指数是青年CSF独立危险因素,TyG指数增高可能促进青年CSF的发生发展。Objective To discuss the correlation between the index oftriglyceride-glucose(TyG)and coronary slow flow(CSF)in young patients.Methods The young patients with CSF diagnosed by coronary angiography(CAG,n=86,aged 18≤age≤44)were chosen into CSF group from Department of Cardiology in the 305th Hospital of Chinese PLA General Hospital from Jan.2017 to Jan.2019.At the same time the young patients without organic coronary stenosis and CSF(n=84)were chosen into control group(NCSF group).The clinical materials,medical history,laboratory data and CAG results were collected,and TyG index was calculated and compared in 2 groups.The risk factors for CSF occurrence in young patients were determined by using multi-factor Logistic regression analysis.The correlationbetweencorrected TIMI frame counts(CTFC)and TyG index was analyzed by using Pearson method.Results The level of body mass index(BMI),proportion of hypertension,total cholesterol level and TyG index were higher in CSF group than those in NCSF group(P<0.05).The results of Logistic multi-factor Logistic regression analysis showed that TyG index was an independent risk factor for CSF occurrence in young patients(OR=1.984,95%CI:1.044-3.012,P<0.05).The results of Pearson analysis showed that CTFC was positively correlated to TyG index(r=0.496,P<0.05).Conclusion TyG index is an independent risk factor for CSF occurrence in young patients,and increased TyG index can improve CSF occurrence and development.

关 键 词：冠状动脉慢血流 青年 甘油三酯葡萄糖指数 胰岛素抵抗 

分 类 号：R543.3[医药卫生—心血管疾病]