微量有机综合实验:丁香花中丁香酚的提取及异构化  

A Microscale Comprehensive Organic Experiment:Extraction and Isomerization of Eugenol from Lilac

作　　者：杨芮 田冬 魏亦军 YANG Rui;TIAN Dong;WEI Yijun

机构地区：[1]安徽医科大学药学院,安徽合肥230032 [2]淮南师范学院化学与材料工程学院,安徽淮南232001

出　　处：《淮南师范学院学报》2024年第5期132-136,共5页Journal of Huainan Normal University

基　　金：安徽省质量工程教学研究项目"药物分析课程线上线下混合式教学改革效果研究"(2023jyxm0246);安徽省教育教学研究项目"SAP模式下有机化学实验教学的改革、实践与评价"(2014jyxm310)。

摘　　要：文章介绍了一个新的有机化学综合实验:从天然产物丁香花中提取丁香酚,以丁香花为原料,利用水蒸气蒸馏提取了一种重要的原料产品——丁香酚。在催化条件下,对提取产物进行异构化反应,得到了异丁香酚,并利用傅里叶变换红外光谱仪和核磁共振波谱仪对产品的结构进行表征。该实验不仅考核了蒸馏、萃取、洗涤和干燥等基本实验操作方法,又考核了对大型分析仪器设备的使用,对提升学生的综合实验技能和管理能力具有重要意义。A new comprehensive experiment of organic chemistry on the extraction of eugenol from the natural product lilac is introduced in this paper.Eugenol,an important raw material,was extracted from lilac by steam distillation.Isoeugenol was obtained by isomerization of the extracted product under catalytic conditions,and the structure of the product was characterized by fourier transform infrared spectrometer and nuclear magnetic resonance spectrometer.The experiment not only examined the basic experimental operations such as distillation,extraction,washing and drying,but also inspected the use of large-scale analytical instruments,which is of great significance to improve students’comprehensive experimental skills and management ability.

关 键 词：有机化学实验 丁香花 丁香酚 异丁香酚 

分 类 号：R917[医药卫生—药物分析学]