Efficient,rapid and incremental extraction of bioactive compounds from the flowers of Hibiscus manihot L.  

作　　者：Juzhao Liu Yujie Fu Qi Cui 

机构地区：[1]College of Pharmaceutical Science,Zhejiang Chinese Medical University,Hangzhou 311402,PR China [2]College of Biological Sciences and Technology,Beijing Forestry University,No.35,Tsinghua East Road,Haidian District,Beijing 100083,PR China

出　　处：《Beverage Plant Research》2023年第1期93-100,共8页饮料植物研究（英文）

基　　金：support from China Postdoctoral Science Foundation(2021M692893,2021M702927);National Natural Science Fund of China(82204552);Natural Science Foundation of Zhejiang Province(LQ22H280007);Research Project of Zhejiang Chinese Medical University(2022JKZKTS10);Zhejiang Province Traditional Chinese Medicine Science and Technology(2023ZR079,2023ZR087).

摘　　要：Flavonoids are the primary functional components in the flowers of Hibiscus manihot L.(HMLF).In this study,an efficient and green ionic liquid-high-speed homogenization coupled with microwave-assisted extraction(IL-HSH-MAE)technique was firstly established and implemented to extract seven target flavonoids from HMLF.Single-factor experiments and Box-Behnken design(BBD)were utilized to maximize the extraction conditions of IL-HSH-MAE,which were as follows:0.1 M of[C4mim]Br,homogenate speed of 7,000 rpm,homogenate time of 120 s,liquid/solid ratio of 24 mL/g,extraction temperature of 62℃and extraction time of 15 min.The maximal total extraction yield of seven target flavonoids attained 22.04 mg/g,which was considerably greater than the yields obtained by IL-HSH,IL-MAE,60%ethanol-HSH-MAE and 60%ethanol-MAE.These findings suggested that the IL-HSH-MAE method can be exploited as a rapid and efficient approach for extracting natural products from plants.The process also possesses outstanding superiority in being environmentally friendly and having a high extraction efficiency and is expected to be a luciferous prospect extraction technology.

关 键 词：INCREMENTAL utilized MAXIMAL 

分 类 号：R284.2[医药卫生—中药学]