元胡止痛滴丸和布洛芬对原发性痛经患者的疼痛症状及焦虑的疗效比较  

Comparison of the efficacy of Yuanhu Zhitong dropping pill and ibuprofen on pain symptoms and mood in patients with primary dysmenorrhea

作　　者：王学智 王海棠 奚宇杰 WANG Xuezhi;WANG Haitang;XI Yujie(Department of General Medicine,Shanggang Community Health Service Center of Pudong New District,Shanghai 200126,China)

机构地区：[1]上海市浦东新区上钢社区卫生服务中心全科医学科,上海200126

出　　处：《世界临床药物》2024年第9期914-918,共5页World Clinical Drug

基　　金：上海市浦东新区卫生健康委员会优秀青年医学人才培养计划(PWRq2021-39)。

摘　　要：目的 观察元胡止痛滴丸和布洛芬对原发性痛经(primary dysmenorrhea,PD)经期疼痛及焦虑的影响。方法 选择2023年1月至12月上钢社区卫生服务中心妇产科门诊PD患者80例,随机分为两组,各40例。元胡止痛滴丸组予元胡止痛滴丸口服,布洛芬组予布洛芬口服,月经D1开始连续服用3 d,共治疗5个月经周期。采用视觉模拟评分法、疼痛时间及汉密尔顿焦虑量表比较患者治疗前后及随访期的疼痛程度及焦虑状态。结果 治疗后及随访期,元胡止痛滴丸组和布洛芬组疼痛评分、疼痛时间及焦虑评分均较前改善(P<0.001)。组间比较显示,治疗后及随访期,布洛芬组疼痛评分、疼痛时间及焦虑评分均显著低于元胡止痛滴丸组(P<0.001)。结论 元胡止痛滴丸和布洛芬均可有效减轻PD的疼痛和焦虑,布洛芬对疼痛发作期的效果优于元胡止痛滴丸。Objective To observe and compare the effects of Yuanhu Zhitong dropping pill and ibuprofen on pain and anxiety in patients with primary dysmenorrhea(PD).Methods Eighty patients with PD in the obstetrics and gynecology outpatient department of Shanggang community health service center from January to December 2023 were selected and randomly divided into the Yuanhu Zhitong dropping pill group and the ibuprofen group,with 40 patients in each group.The Yuanhu Zhitong dropping pill group was given oral administration of Yuanhu Zhitong dropping pill and the ibuprofen group was given oral ibuprofen for three consecutive days starting from the first day of menstruation for a total of five menstrual cycles.Visual analogue score(VAS),pain time and Hamilton anxiety scale were used to compare the pain and anxiety status of the two groups before,after treatment and the follow-up period.Results Compared with before treatment,the pain scores,pain duration and anxiety scores of patients in Yuanhu Zhitong dropping pill group and ibuprofen group significantly improved after treatment and during the follow-up period(P<0.001).The comparison between the two groups showed that after treatment and during follow-up,the pain score,pain duration,and anxiety score in the ibuprofen group were significantly lower than those in the Yuanhu Zhitong dropping pill group(P<0.001).Conclusion Both Yuanhu Zhitong dropping pill and ibuprofen can effectively reduce pain and improve anxiety in patients with PD,and ibuprofen is more effective than Yuanhu Zhitong dropping pill for pain episodes.

关 键 词：元胡止痛滴丸 布洛芬 原发性痛经 疼痛 

分 类 号：R711.51[医药卫生—妇产科学]