中国医院药物警戒系统在某市的推广及应用效果分析  

Analysis of the Promotion and Application Effect of Chinese HospitalPharmacovigilance System

作　　者：洪志鑫 HONG Zhi-xin(Quanzhou Food and Drug Certification and Adverse Reaction Monitoring Center Quanzhou,Quanzhou 362000,China)

机构地区：[1]泉州市食品药品认证与不良反应监测中心,福建泉州362000

出　　处：《海峡药学》2024年第9期132-134,共3页Strait Pharmaceutical Journal

摘　　要：目的介绍中国医院药物警戒系统(CHPS)的功能和前期准备工作,探究CHPS在市级辖区医院的应用效果,进而为更多市级监测机构推广CHPS提供经验。方法分别收集辖区内三家国家哨点医院的药品不良反应报告,比较CHPS应用前后2年内的上报例数和报告类型的差异。结果CHPS实现了药品不良反应辅助快速上报、主动监测、智能搜索、重点监测和信息反馈等功能等功能,药品不良反应报告数量和质量得到明显增加。结论CHPS的应用可提高医院药品不良反应监测水平,为加强药品上市后安全性监管奠定信息基础。OBJECTIVE The paper Introduces the functions and preliminary pr eparations of the Chinese Hospital Pharmacovigilance System(CHPS),and explores the application effect of CHPS in hospitals in municipal districts,so as to pr ovide experience for more municipal monitoring institutions to promote CHPS.METHODS The ADR reports of three national sentinel hospitals were collected respectively,and the differences in the number of reported cases and types within 2 years before and after the application of CHPS were compared and analyzed.RESULTS CHPS implements functions such as ADR-assist ed rapid reporting,active monitoring,intelligent search,key monitoring and in formation feedback,and the quantity and quality of ADR reports have been signif icantly increased.CONCLUSION The application of CHPS can impro ve the ADR monitoring level in hospitals and lay an information foundation for s trengthening the safety supervision of the post-marketing drugs.

关 键 词：中国医院药物警戒系统 CHPS 药品不良反应监测 

分 类 号：R969.4[医药卫生—药理学]