电阻抗断层成像指导机械通气呼吸末正压设置的研究进展  

Research progress on electrical impedance tomography guiding positive end-expiratory pressure setting during mechanical ventilation

作　　者：宋礼坡[1] 王春梅[1] SONG Lipo;WANG Chunmei(Department of Critical Care Medicine,Xuanwu Hospital of Capital Medical University,Beijing 100053,China)

机构地区：[1]首都医科大学宣武医院重症医学科,北京100053

出　　处：《基础医学与临床》2024年第11期1492-1498,共7页Basic and Clinical Medicine

基　　金：北京市重大疫情防治重点专科项目(京卫医〔2021〕135号);国家临床重点专科建设项目(国卫办医函〔2021〕451号)。

摘　　要：目前机械通气设置最佳呼气末正压(PEEP)的策略仍需要进一步临床探索,电阻抗断层成像(EIT)是20世纪末新发展的临床技术,能够实时监测肺通气等,有助于临床应用来探索最佳PEEP的设置。本综述重点总结了近几年发表的使用EIT指导PEEP设定的原理,通过监测呼吸系统顺应性、空间分布、时间分布、局部肺灌注等信息设定PEEP,以及分析了用此方法设定PEEP的效果和/或使用EIT进行个体化PEEP设置的相关基础与临床研究信息。At present,the strategy of setting the optimal positive end-expiratory pressure(PEEP)for mechanical ventilation still needs further clinical exploration.Electrical impedance tomography(EIT)is a newly developed technology at the end of the 20th century.It can monitor pulmonary ventilation in real time,so is extensively important to optimal PEEP setting.This review summarizes the principles of using EIT to guide PEEP setting,monitoring respiratory system compliance,spatial distribution,temporal distribution,local lung perfusion and other information published in recent years,analyzes the basic and clinical research information related to PEEP effect and its application in individualized PEEP setting.

关 键 词：电阻抗断层成像 机械通气 呼吸末正压 呼吸机相关肺损伤 

分 类 号：R563[医药卫生—呼吸系统]