细胞移植联合其他治疗策略在治疗白癜风中的研究进展  

Advances in cell transplantation combined with other therapeutic strategies in the treatment for vitiligo

作　　者：刘尚昆 王红娟[2] 康晓静[2] LIU Shangkun;WANG Hongjuan;KANG Xiaojing(Graduate School of Xinjiang Medical University,Urumqi 830001;Department of Dermatology and Venereology,People's Hospital of Xinjiang Uygur Autonomous Region,Xinjiang Clinical Medical Research Center for Dermatologic Diseases,Xinjiang Key Laboratory of Dermatology Research(XJYS1707),Urumqi 830001,China)

机构地区：[1]新疆医科大学研究生院,新疆乌鲁木齐830001 [2]新疆维吾尔自治区人民医院皮肤性病科、新疆皮肤病临床医学研究中心、新疆皮肤病研究重点实验室(XJYS1707),新疆乌鲁木齐830001

出　　处：《基础医学与临床》2024年第11期1584-1588,共5页Basic and Clinical Medicine

基　　金：国家自然科学基金(82173406)。

摘　　要：白癜风是一种以黑素细胞数量减少或功能丧失为特征的获得性色素脱失性皮肤病。目前白癜风常规治疗手段有药物治疗、光疗及外科治疗。细胞移植作为治疗白癜风的一种重要外科手段,对于稳定期、局限型或其他方法治疗无效的白癜风疗效确切,但复色率差异较大。如何最大程度实现难治性白癜风患者皮损复色,联合治疗是较好选择。近年来,关于细胞移植联合策略的相关报道逐渐增多,为提高白癜风患者的皮损复色率带来新的希望。本文对细胞移植联合策略的应用进展进行综述,旨在为难治性白癜风临床治疗提供更多选择。Vitiligo is an acquired depigmentation skin disease characterized by a decrease or loss of function of melanocytes.The conventional treatment for vitiligo include drug therapy,phototherapy and surgical treatment.As an important surgical treatment for vitiligo,cell transplantation is effective especially for the case which is stable,limited or fail to respond to other methods,but the recoloration rate varies greatly.The combination therapy is a better choice to maximize the recoloration of skin lesions in patients with refractory vitiligo.In recent years,reports on the combined strategy of cell transplantation have gradually increased,bringing new hope to improve the rate of discoloration of vitiligo patients.This paper reviews the progress of the application of cell transplantation combination strategy aiming for providing more options for the clinical treatment of refractory vitiligo.

关 键 词：白癜风 细胞移植 联合治疗 黑素细胞 

分 类 号：R758.41[医药卫生—皮肤病学与性病学]