阿司匹林多效性研究进展  

Progress in the Multiple-effect Study of Aspirin

作　　者：罗欢 高健美 龚其海 LUO Huan;GAO Jianmei;GONG Qihai(Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education;School of Pharmacy,Zunyi Medical University,Zunyi 563000,China)

机构地区：[1]遵义医科大学基础药理教育部重点实验室暨特色民族药教育部国际合作联合实验室,遵义563000 [2]遵义医科大学药学院,遵义563000

出　　处：《医药导报》2024年第11期1822-1826,共5页Herald of Medicine

基　　金：贵州省中药民族药2011协同创新中心(黔教技[2022]026号)。

摘　　要：阿司匹林是在临床上广泛应用的非甾体解热镇痛抗炎药,其疗效确切,不良反应较少。近期研究发现,阿司匹林除具有解热镇痛抗炎作用外,还有显著的抗肿瘤、抗心血管系统疾病、抗肌肉骨骼系统疾病、抗神经系统疾病等作用。该文结合国内外相关研究报道,综述阿司匹林对肿瘤、心血管疾病、肌肉骨骼系统疾病、神经系统疾病的治疗作用及其可能的作用机制,旨在为阿司匹林的临床合理应用并发现其新的药理作用提供线索和依据。Aspirin,a non-steroidal anti-inflammatory drug,is widely used in clinics with definite therapeutic effects and a few adverse drug reactions.Recent studies demonstrated that other effects besides antipyretic,analgesic,and anti-inflammatory effects have been discovered,such as anti-cancer,anti-cardiovascular diseases,anti-skeletal muscle diseases,and anti-nervous system diseases.This paper reviewed the therapeutic effects and possible mechanisms of aspirin on cancer,cardiovascular disease,muscle-skeletal disease,and nervous system disease based on the related research status at home and abroad.It will provide clues and a theoretical basis for clinical rational drug use and discover novel pharmacological effects of aspirin in the future.

关 键 词：阿司匹林 肿瘤 心血管系统疾病 肌肉骨骼系统疾病 神经系统疾病 

分 类 号：R973.2[医药卫生—药品] R965[医药卫生—药学]