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作 者:冯敏贤[1] 岑秀娴 Feng Minxian;Cen Xiuxian(Hematopoietic Stem Cell Transplantation Ward,No.5 Department of Pediatrics,Sun Yat-sen Memorial Hospital,Sun Yat-sen University,Guangzhou 510000,China)
机构地区:[1]中山大学孙逸仙纪念医院儿科五区造血干细胞移植病区,广州510000
出 处:《国际医药卫生导报》2024年第22期3838-3840,共3页International Medicine and Health Guidance News
基 金:广东省基础与应用基础研究基金(2024A1515011740)。
摘 要:本研究回顾性分析2例患儿在造血干细胞移植预处理阶段中,使用兔抗人胸腺细胞免疫球蛋白(rATG)出现严重过敏性休克现象。经验总结包括:全面评估病史,精准识别过敏风险;规范用药流程,严格执行预防措施;常态化应急演练,确保快速高效抢救;实施人文关怀,缓解焦虑情绪。经过及时有效的抢救治疗,2例患儿均顺利度过预处理阶段,成功完成造血干细胞移植手术,分别在术后28 d和23 d好转出院。This study retrospectively analyzed and explored the severe allergic shock phenomenon that occurred in two children during the pre-treatment stage of hematopoietic stem cell transplantation when using rabbit anti-human thymocyte immunoglobulin(rATG).Summary of experiences included:comprehensive evaluation of medical history,precise identification of allergic risk;standardizing the medication process and strictly implementing preventive measures;normalized emergency drills to ensure rapid and efficient rescue;implementing humanistic care to alleviate the anxiety.After timely and effective rescue treatment,both children successfully passed the pre-treatment phase of medication and completed hematopoietic stem cell transplantation surgery.They were improved and discharged at 28 and 23 days after surgery,respectively.
关 键 词:造血干细胞移植 兔抗人胸腺细胞免疫球蛋白 过敏性休克 护理
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