514名使用合成毒品的男男性行为者HIV暴露前预防用药意愿及其影响因素分析  

Analysis of willingness and influencing factors of pre-exposure prophylaxis among 514 men who have sex with men who use synthetic drugs

作　　者：张慧颖 孟庆芬 王肖盟 黄鹏翔[2] ZHANG Hui-ying;MENG Qing-fen;WANG Xiao-meng;HUANG Peng-xiang(AIDS Prevention and Control Department,Yanggu County Center for Disease Control and Prevention,Shandong 252300,China;Section of Scientific Research and Education,Shandong Center for Disease Control and Prevention)

机构地区：[1]阳谷县疾病预防控制中心艾滋病防制科,山东252300 [2]山东省疾病预防控制中心科研教育部

出　　处：《预防医学论坛》2024年第8期597-601,共5页Preventive Medicine Tribune

摘　　要：目的 了解使用合成毒品的男男性行为者艾滋病病毒(HIV)暴露前预防用药(PrEP)的使用意愿及影响因素,为HIV暴露前预防用药的推广提供参考依据。方法 2022年4-7月在山东省男男性行为人群(MSM)艾滋病监测哨点调查514名MSM,采用问卷调查收集吸食合成毒品的MSM社会人口学、性行为、合成毒品使用、暴露前预防药物使用意愿等信息,采用χ~2检验和多因素logistic回归模型分析暴露前预防药物使用意愿及影响因素。结果 514名MSM的平均年龄(30.38±8.67)岁,47.86%(246/514)为平均每周使用一次以上合成毒品,72.57%(373/514)愿意使用暴露前预防药物,69.26%(356/514)周围有人服用暴露前预防用药,15.56%(80/514)使用过暴露前预防用药。多因素logistic回归分析显示,通过互联网/交友软件寻找男伴(OR=2.47,95%CI:1.32~4.64)、最近一年做过艾滋病检测(OR=3.39,95%CI:1.23~9.33)、听说过PrEP(OR=5.32,95%CI:2.97~9.54)、周围有人使用PrEP(OR=2.17,95%CI:1.18~3.98)的MSM使用PrEP的意愿更强烈(P<0.05)。结论 使用合成毒品的MSM对PrEP的使用意愿较高但使用率低,通过互联网/交友软件寻找男伴、通过互联网/交友软件寻找男伴、最近一年做过艾滋病检测、听说过PrEP、周围有人使用PrEP是MSM PrEP使用意愿的影响因素。Objective To investigate the willingness to use pre-exposure prophylaxis(PrEP)for HIV among men who have sex with men(MSM)who use synthetic drugs as well as the influencing factors,so as to provide a reference for the promotion of PrEP.Methods A survey was conducted among 514 MSM at an AIDS surveillance sentinel site in Shandong province from April to July 2022.Questionnaires were used to collect information on sociodemographic characteristics,sexual behavior,synthetic drug use,and willingness to use PrEP.Chi-square tests and multivariate logistic regression models were employed to analyze the willingness to use PrEP and its influencing factors.Results The average age of the 514 MSM was(30.38±8.67)years.Among them,47.86%(246/514)reported using synthetic drugs more than once a week,72.57%(373/514)expressed willingness to use PrEP,69.26%(356/514)had someone around them who had used PrEP,and 15.56%(80/514)had used PrEP themselves.Multivariate logistic regression analysis revealed that MSM who sought male partners through the internet/dating apps(OR=2.47,95%CI:1.32-4.64),had undergone HIV testing in the past year(OR=3.39,95%CI:1.23-9.33),had heard of PrEP(OR=5.32,95%CI:2.97-9.54),and had someone around them using PrEP(OR=2.17,95%CI:1.18-3.98)were more willing to use PrEP(P<0.05).Conclusion MSM who use synthetic drugs have a high willingness but low usage rate of PrEP.Factors influencing their willingness to use PrEP include seeking male partners through the internet/dating apps,having undergone HIV testing in the past year,having heard of PrEP,and having someone around them using PrEP,according to authoritative sources such as academic research and public health reports.

关 键 词：男男性行为者 艾滋病 合成毒品 暴露前预防 影响因素 

分 类 号：R512.91[医药卫生—内科学] R978.7[医药卫生—临床医学]