土茯苓、省头草药对治疗湿热蕴结型代谢相关脂肪性肝病经验  

Experience on treating damp⁃heat accumulation syndrome in metabolic associated fatty liver disease with herbal pair of Tufuling and Shengtoucao

作　　者：石佳 余卓[2] SHI Jia;YU Zhuo(Institute of Infectious Diseases,Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Department of Liver Diseases,Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China)

机构地区：[1]上海中医药大学附属曙光医院传染病研究所,上海201203 [2]上海中医药大学附属曙光医院肝病科,上海201203

出　　处：《上海中医药杂志》2024年第10期59-62,共4页Shanghai Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金项目(82222074,82074154);上海市教育发展基金会、上海市教育委员会“曙光计划”项目(23SG38);上海市委组织部青年拔尖人才计划项目(2020年);国家中医药管理局高水平中医药重点学科建设项目(ZYYZDXK-202306);上海市卫健委高月求上海市名老中医学术经验研究工作室建设项目(SHGZS-202246)。

摘　　要：代谢相关脂肪性肝病(MAFLD)的核心病机为本虚标实,本虚为肝脾肾亏虚,标实则以痰、湿、瘀、热为要,临床常见湿热壅盛之象。土茯苓、省头草是临床治疗湿热蕴结型MAFLD的常用药对,二药配伍内外、上中下三焦同治,可清化痰湿秽浊、健脾和中。灵活使用土茯苓、省头草药对,可有效改善MAFLD患者的湿热证候。并附验案1则。The core pathogenesis of metabolic associated fatty liver disease(MAFLD)is deficiency in the root and excess in manifestations.The root deficiency pertains to deficiency of the liver,spleen,and kidneys,while the excess in manifestations is predominantly marked by phlegm,dampness,stasis,and heat,often presenting as damp-heat accumulation syndrome clinically.Tufuling(Smilacis Glabrae Rhizoma)and Shengtoucao(Melilotus Suaveolens Ledeb)are frequently used in combination to treat damp-heat accumulation syndrome in MAFLD.This herbal pair addresses both internal and external factors,and treat the upper,middle,and lower energizers simultaneously,effectively clearing phlegm,dampness,and filthy turbidity,while also strengthening the spleen and harmonizing the middle energizer.The flexible application of this herbal pair can significantly alleviate dampheat symptoms in patients with MAFLD.A proven case is included for illustration.

关 键 词：代谢相关脂肪性肝病 非酒精性脂肪性肝病 湿热蕴结证 土茯苓 省头草 佩兰 药对 中医药疗法 

分 类 号：R259[医药卫生—中西医结合]