中药抗胃溃疡质量标志物的研究进展  

Research progress on quality markers of traditional Chinese medicine for gastric ulcer

作　　者：陈智兰 黄少敏 覃金桥 赵天琪 谢旭格 牛新迈 秦华珍[1] CHEN Zhilan;HUANG Shaomin;QIN Jinqiao;ZHAO Tianqi;XIE Xuge;NIU Xinmai;QIN Huazhen(Guangxi University of Traditional Chinese Medicine,Nanning 530200,Guangxi)

机构地区：[1]广西中医药大学,广西南宁530200

出　　处：《中药与临床》2024年第4期120-124,共5页Pharmacy and Clinics of Chinese Materia Medica

基　　金：国家自然科学基金项目(82074034)。

摘　　要：通过查阅文献资料,对中药抗胃溃疡质量标志物的研究进行梳理总结,基于中药质量标志物(Q-marker)的核心概念,从传统药性、功效、入血成分、化学成分可测性、不同配伍中表达成分、肠道菌群和网络药理学的路径,对此类中药的质量标志物进行预测,初步确定了抗胃溃疡中药质量标志物的备选化合物,可为中医药治疗胃溃疡提供参考。By consulting the literature,the research on the quality markers of traditional Chinese medicine against gastric ulcer was summarized.Based on the core concept of quality markers of traditional Chinese medicine(Q-marker),the quality markers of traditional Chinese medicine were predicted from the aspects of traditional medicinal properties,efficacy,components detected in blood,chemical composition measurability,expression components in different combinations,intestinal flora and network pharmacology,and the alternative compounds of quality markers of traditional Chinese medicine against gastric ulcer were preliminarily determined,which could provide reference for the treatment of gastric ulcer with traditional Chinese medicine.

关 键 词：中药 抗胃溃疡 质量标志物 研究进展 

分 类 号：R285.5[医药卫生—中药学]