基于MRE评分法评估溃疡性结肠炎活动性严重程度的研究  

Study on the evaluation of the severity of ulcerative colitis activity based on MRE scoring

作　　者：刘晓曦 袁世好 袁爽 张国良 唐明忠 LIU Xiaoxi;YUAN Shihao;YUAN Shuang;ZHANG Guoliang;TANG Mingzhong(Department of Radiology,Xiushan Tujia and Miao Autonomous County People's Hospital,Chongqing 409900,China)

机构地区：[1]秀山土家族苗族自治县人民医院放射科,重庆409900

出　　处：《影像研究与医学应用》2024年第21期18-22,共5页Journal of Imaging Research and Medical Applications

基　　金：重庆市卫生健康委医学科研项目(2023WSJK060)。

摘　　要：目的:探讨磁共振小肠成像(MRE)评分法评估溃疡性结肠炎(UC)严重程度的价值。方法:选取秀山土家族苗族自治县人民医院2022年1月—2024年6月收治的18例接受了MRE检查及结肠镜检查的UC患者。根据改良Mayo(mMayo)评分,将患者分为四组:临床缓解组(3例)、轻度组(4例)、中度组(9例)和重度组(2例)。计算每例患者的累积MRE评分,并分析其与mMayo评分的相关性。结果:临床缓解与中度组间T_1WI增强序列肠壁中-明显强化、弥散加权成像(DWI)稍高-高信号、表观弥散系数(ADC)图稍低-低信号、肠壁周围血管增生、溃疡形成、系膜区淋巴结肿大比较差异有统计学意义(P<0.05)。轻度与中度组间DWI稍高-高信号、ADC图稍低-低信号、系膜区淋巴结肿大差异有统计学意义(P<0.05)。轻度与重度组间系膜区淋巴结肿大差异有统计学意义(P=0.007)。临床缓解、轻度、中度、重度组MRE评分分别为(2.3±1.5)分、(4.8±1.5)分、(8.9±1.8)分、(11.0±0.0)分,四组间差异有统计学意义(P<0.001)。MRE评分与改良Mayo评分呈正相关(r=0.841,P<0.001)。结论:通过MRE评分法评估的UC活动性严重程度与mMayo评分的活动性严重程度呈强正相关。MRE评分系统可能是UC活动性严重程度评估的潜在预测指标。Objective Exploring the value of magnetic resonance enterography(MRE)scoring method in assessing the severity of ulcerative colitis(UC).Methods 18 UC patients who underwent MRE examination and colonoscopy in Xiushan Tujia and Miao Autonomous County People's Hospital from January 2022 to June 2024 were included.According to the modified Mayo(mMayo)score,the patients were divided into four groups:clinical remission group(3 patients),mild group(4 patients),moderate group(9 patients)and severe group(2 patients).The cumulative MRE score of each patient was calculated,and its correlation with the mMayo score was analyzed.Results There were statistically significant differences in T1WI enhanced sequence intestinal wall moderate-obvious enhancement,diffusion weighted imaging(DWI)slightly high-high signal,apparent diffusion coeffecient(ADC)map slightly low-low signal,intestinal wall perivascular hyperplasia,ulcer formation,and mesangial lymphadenopathy between the clinical remission and moderate groups(P<0.05).There were statistically significant differences in DWI slightly high-high signal,ADC map slightly low-low signal,and mesangial lymphadenopathy between the mild and moderate groups(P<0.05).There was also a significant difference in mesangial lymphadenopathy between the mild and severe groups(P=0.007).The MRE scores of the clinical remission,mild,moderate,and severe groups were(2.3±1.5),(4.8±1.5),(8.9±1.8),and(11.0±0.0),respectively,and the differences among the four groups were statistically significant(P<0.001).The MRE score was positively correlated with the mMayo score(r=0.841,P<0.001).Conclusion The severity of UC activity assessed by the MRE scoring method is strongly positively correlated with the severity of activity of the mMayo score.The MRE scoring system may be a potential predictive indicator for the assessment of the severity of UC activity.

关 键 词：溃疡性结肠炎 疾病活动性 MRE 改良Mayo评分 

分 类 号：R445.2[医药卫生—影像医学与核医学]