弥散加权成像联合磁共振动态增强-时间信号强度曲线对乳腺良恶性肿块的诊断价值研究  

The diagnostic value of diffusion-weighted imaging combined with time-intensity-curve(TIC)analysis of dynamic contrast-enhanced(DCE)MRI in the diagnosis of benign and malignant breast masses

作　　者：邱海燕 陈琳徽 QIU Haiyan;CHEN Linhui(Department of Radiology,The Central Hospital of Yongzhou,Yongzhou,Hunan 425000,China)

机构地区：[1]永州市中心医院放射科,湖南永州425000

出　　处：《影像研究与医学应用》2024年第21期26-28,32,共4页Journal of Imaging Research and Medical Applications

摘　　要：目的:探讨弥散加权成像(DWI)联合磁共振动态增强-时间信号强度曲线(DCE-TIC)对乳腺良恶性肿块的诊断效果。方法:选取永州市中心医院2022年3月—2024年3月收治的109例乳腺肿块患者为研究对象,患者术前均进行DWI及DCE-MRI扫描,对比分析良恶性肿块在影像学、TIC分布及表观弥散系数(ADC)值等方面的差异,以病理结果为金标准,统计DWI、DCE-TIC单一检查及两者联合检查对乳腺良恶性肿块诊断的灵敏度、特异度和准确率。结果:DWI联合DCE-TIC诊断乳腺良恶性肿块的灵敏度、特异度和准确率均高于单一检查。且良恶性肿块在形态学、TIC分布及ADC值等方面比较,差异有统计学意义(P<0.05)。结论:DWI联合DCE-TIC在乳腺良恶性肿块的诊断中具有更高的诊断价值。Objective To explore the diagnostic effect of diffusion weighted imaging(DWI)combined with time-intensity-curve(TIC)analysis of dynamic contrast-enhanced(DCE)MRI on benign and malignant breast masses based on morphology.Methods 109 patients with breast masses admitted to Yongzhou Central Hospital from March 2022 to March 2024 were selected as the research subjects.All patients underwent routine MRI sequence scanning,DWI and DCE-MRI before surgery to compare and analyze the differences in imaging(morphology,boundary,enhancement,adjacent structure),TIC distribution,and apparent diffusion coeffecient(ADC)value between benign and malignant tumors.Relevant data were organized,and pathological results were used as the gold standard to statistically analyze the sensitivity,specificity and accuracy of DWI,DCE-TIC single detection,and their combined detection for the diagnosis of breast benign and malignant tumors.Results The sensitivity,specificity,and accuracy of the combined diagnosis of benign and malignant breast masses based on morphology were higher than those of single detection.Moreover,there were significant differences in morphology,TIC distribution,and ADC values between benign and malignant tumors,and the differences were statistically significant(P<0.05).Conclusion On the basis of morphology,the combination of DWI and DCE-TIC has higher diagnostic value in the diagnosis of benign and malignant breast masses.

关 键 词：乳腺癌 弥散加权成像 表观弥散系数 磁共振动态增强 

分 类 号：R445.2[医药卫生—影像医学与核医学]