医源性肉毒中毒预防和护理的最佳证据总结  

Summary of the best evidence for prevention and nursing of iatrogenic botulism

作　　者：陈洁 全舒萍[1] 王玲[1] 王秀丽[1] Chen Jie;Quan Shuping;Wang Ling;Wang Xiuli(Breast and Thyroid Plastic Surgery Department,Peking University Shenzhen Hospital,Guangdong Province,Shenzhen 518000,China)

机构地区：[1]北京大学深圳医院乳甲整形外科,深圳518036

出　　处：《药物不良反应杂志》2024年第10期588-593,共6页Adverse Drug Reactions Journal

摘　　要：目的:总结医源性肉毒中毒预防和护理相关证据。方法:系统检索国内外相关网站及医学文献数据库中关于医源性肉毒中毒预防、护理和管理的相关文献(截至2023年12月30日);采用循证方法对文献进行质量评价、证据提取与汇总。结果:共纳入14篇文献,包括指南1篇,专家共识6篇、系统评价4篇及临床决策3篇,整体质量均高。经过汇总与分析,共梳理出医源性肉毒中毒预防和护理的循证证据包括预防与管理、健康教育、预警与评估、药物治疗管理、支持性护理、功能锻炼和心理护理7个主题41条证据。结论:采用循证方法总结的医源性肉毒中毒预防和护理证据,总体质量较高,推荐意见对临床护理具有较高的参考价值。Objective To summarize the evidence related to the prevention and nursing of iatro-genic botulism.Methods The relevant literature on prevention,nursing and management of iatrogenic botulinum in relevant websites and medical literature databases at home and abroad were systematically searched(up to December 30,2023).Evidence-based methods were used to evaluate the quality of literature and conduct extraction and summarization of the evidence.Results A total of 14 literature was included,including 1 guideline,6 expert consensus,4 systematic reviews and 3 clinical decisions,all of which were of high overall quality.After summary and analysis of the evidence,a total of 7 evidence topics and 41 evidence-based evidences for the prevention and nursing of iatrogenic botulism were sorted out,including prevention and management,health education,early warning and evaluation,drug treatment management,supportive nursing,functional exercise,and psychological nursing.Conclusion The evidence of pre-vention and nursing of iatrogenic botulinum summarized by evidence-based method has a high overall quality,and the recommendations have high reference value in clinical nursing.

关 键 词：肉毒毒素类 中毒 医源性疾病 护理研究 循证医学 证据总结 

分 类 号：R473.5[医药卫生—护理学]