一起残疾人福利院新型冠状病毒XBB.1.9.1变异株暴发疫情的调查研究  

Investigation on an outbreak of SARS-CoV-2 XBB.1.9.1 variant in a welfare home for the disabled

作　　者：岑权新 陈琴 周曹 叶浩风[1] 梁广 陈昌明[1] 程晓宁[1] 郭常春 陆剑云 陈纯[2] CEN Quanxin;CHEN Qin;ZHOU Cao;YE Haofeng;LIANG Guang;CHEN Changming;CHENG Xiaoning;GUO Changchun;LU Jianyun;CHEN Chun(Baiyun Center for Disease Control and Prevention,Guangzhou,Guangdong 510440,China;不详)

机构地区：[1]广州市白云区疾病预防控制中心,广东广州510440 [2]广州市疾病预防控制中心,广东广州510440

出　　处：《中国病毒病杂志》2024年第4期385-387,共3页Chinese Journal of Viral Diseases

基　　金：广州市科技计划项目(2023A03J0938)。

摘　　要：目的 对某残疾人福利院发生的一起由新型冠状病毒XBB. 1.9.1变异株感染引起的暴发疫情的调查处置情况进行分析,为特殊集体机构新型冠状病毒感染疫情防控提供参考依据。方法 采用现场流行病学方法,对2023年5月某残疾人福利院工作人员及服务对象新型冠状病毒感染状况开展流行病学调查及分析。使用实时荧光定量反转录聚合酶链方法(qRT-PCR),对现场采集的口咽拭子样本进行新型冠状病毒核酸检测。通过三代测序平台对新型冠状病毒进行测序,采用Pangolin分型法对新型冠状病毒变异株进行鉴定。结果 该起疫情持续7 d(2023年5月7日至5月13日),累计报告新型冠状病毒感染病例75例,总罹患率为10.47%(75/716)。所有病例均为轻症或无症状,无重症与死亡病例报告。新型冠状病毒基因测序为奥密克戎XBB. 1.9.1和XBB. 1.9.1.2。结论 本起疫情是由工作人员社区感染后进入福利院区引发的新型冠状病毒XBB. 1.9.1变异株暴发疫情。及时、到位的新型冠状病毒防控措施落实与医疗救治,是疫情有效控制的关键。Objective To analyze the investigation and handling of an outbreak in the welfare home for the dis-abled caused by the infection of severe acute respiratory syndrom coronavirus 2(SARS-CoV-2)mutant strain XBB.1.9.1 and provide a reference for the prevention and control of COVID-19 in special collective institu-tions.Methods Using field epidemiological methods,investigation and analysis were carried out on the in-fection of SARS-CoV-2 among the staff and the disabled of the welfare home in May 2023.Real time fluores-cence quantitative RT-PCR(qRT-PCR)method was used to detect SARS-CoV-2 nucleic acid in oropharyn-geal swab samples collected on site.SARS-CoV-2 was sequenced by third generation sequencing platform,and SARS-CoV-2 variants were identified by Pangolin typing method.Results The epidemic lasted for 7 days(from May 7 to May 13,2023).Totally 75 cases of COVID-19 were reported,with a total incidence rate of 10.47%(75/716).All cases were mild or asymptomatic,with no reported severe cases or deaths.The SARS-CoV-2 was sequenced as Omicron XBB.1.9.1 and XBB.1.9.1.2.Conclusions The outbreak of COVID-19 is caused by XBB.1.9.1 variant transmitted by the community-infected welfare home staff.Pre-vention and control measures and medical treatment should be implemented timely and effectively to controlling the epidemic.

关 键 词：新型冠状病毒 聚集性疫情 现场流行病学调查 特殊集体机构 

分 类 号：R183.3[医药卫生—流行病学]