人际心理治疗对HIV感染者抑郁干预效果的Meta分析  

Meta analysis of the effects of interpersonal psychotherapy on depression in patients infected with HIV

作　　者：申兰 张江辉 李颖[3] 王炀 徐丹 李佳 SSHEN Lan;ZHANG Jianghui;LI Ying;WANG Yang;XU Dan;LI Jia(Zhuhai Campus of Zunyi Medical University,Zhuhai 519041,Guangdong,China;The Fifth Affiliated(Zhuhai)Hospital of Zunyi Medical University,Zhuhai 519100,Guangdong,China;The Fifth Affiliated Hospital of Sun Yat-sen University,Zhuhai 519000,Guangdong,China)

机构地区：[1]遵义医科大学珠海校区,广东珠海519041 [2]遵义医科大学第五附属(珠海)医院,广东珠海519100 [3]中山大学附属第五医院,广东珠海519000

出　　处：《中国艾滋病性病》2024年第10期1101-1106,共6页Chinese Journal of Aids & STD

基　　金：2024年度珠海市医学科研项目(2420009000034)。

摘　　要：目的通过Meta分析评价人际心理治疗对HIV感染者抑郁症状的干预效果。方法系统检索中国知网(CNKI)、万方数据知识服务平台(Wangfang Data)、维普数据资讯中文期刊服务平台(VIP)、中国生物医学文献服务系统(SinoMed)、PubMed、Embase、Web of Science、Cochrane library、CINAHL、PsycInfo数据库中人际心理治疗对HIV感染者抑郁实施干预的随机对照试验,检索时间由建库至2024年1月20日,通过RevMan 5.2软件进行统计处理。结果共纳入文献9篇,包括905名HIV感染者。Meta分析结果显示,人际心理治疗可显著降低HIV感染者抑郁症状[SMD=-1.13,95%CI(-1.95~-0.31),P<0.05]及增强患者社会支持[SMD=0.56,95%CI(0.23~0.88),P<0.05],其中抑郁症状的亚组分析显示,干预方式最大效应量为线上干预[SMD=-1.41,95%CI(-1.77~-1.05),P<0.05];干预次数最大效应量为9次[SMD=-3.85,95%CI(-4.45~-3.22),P<0.05];干预人群最大效应量为一般HIV感染者[SMD=-1.68,95%CI(-1.87~-1.48),P<0.05]。结论人际心理治疗可减轻患者抑郁症状,提高患者社会支持,其中线上干预疗效优于现场干预,干预次数为9次疗效最优,一般HIV感染者干预疗效最为显著。Objective To evaluate the effect of interpersonal psychotherapy as an intervention for depressive symptoms in patients with AIDS through a Meta analysis.Methods Systematic searching was conducted for randomized controlled trials of interpersonal psychotherapy intervention for depression in patients with AIDS;databases included CNKI,Wangfang Data,VIP,SinoMed,PubMed,Embase,Web of Science,Cochrane Library,CINAHL,and PsycINFO.The databases were searched from library construction to January 20,2024,and statistical processing was performed using RevMan 5.2 software.Results A total of nine articles were included for an analysis of 905 HIV-infected patients.The results of the meta-analysis showed that interpersonal psychotherapy could significantly reduce depressive symptoms in AIDS patients(SMD=-1.13,95%CI:-1.95--0.31,P<0.05)and enhance patients'social support(SMD=0.56,95%CI:0.23-0.88,P<0.05);further,the subgroup analysis of depressive symptoms showed that the maximum effect size of the intervention method was remote intervention(SMD=-1.41,95%CI:-1.77--1.05,P<0.05).The maximum effect size of the number of interventions was nine times(SMD=-3.85,95%CI:-4.45--3.22,P<0.05);and the maximum effect size of the intervention population included general AIDS patients(SMD=-1.68,95%CI:-1.87--1.48,P<0.05).Conclusions Interpersonal psychotherapy can alleviate depressive symptoms and improve social support.Remote interventions are more effective than on-site interventions.Optimal treatment results are obtained when the number of interventions is 9,and the intervention effect is most significant in patients with AIDS in general.

关 键 词：人际心理治疗 艾滋病 抑郁 META分析 

分 类 号：R512.91[医药卫生—内科学] R373.9[医药卫生—临床医学]