急性冠脉综合征的危险因素分析  

Risk factors of acute coronary syndromes

作　　者：罗来梅 施伟刚 谭伟 王凌云 阎侠 LUO Laimei;SHI Weigang;TAN Wei(Interventional Catheterization Room,Jiangsu Province(Suqian)Hospital,Jiangsu,Suqian 223800,China;不详)

机构地区：[1]江苏省人民医院宿迁医院介入导管室,223800 [2]江苏省人民医院宿迁医院重症医学科,223800 [3]江苏省人民医院宿迁医院心内科,223800

出　　处：《河北医药》2024年第20期3163-3166,3172,共5页Hebei Medical Journal

摘　　要：目的分析急性冠脉综合征的危险因素。方法选取2020年1月至2022年12月在宿迁市第一人民医院接受诊治的855例急性冠脉综合征患者,设为患病组;并纳入同期接受体检健康的855例志愿者,设为未患病组。收集2组一般资料、既往病史、血液指标及生活习惯等资料进行对比分析,应用Logistic回归分析模型对影响急性冠脉综合征的相关因素进行分析。结果应用Logistic回归模型分析急性冠脉综合征的影响多因素发现,BMI≤23.9 kg/m^(2)、饮食习惯为清淡营养、吸烟指数≤400、日酒精摄入量≤15 g为保护因素(OR<1,P<0.05);冠心病、糖尿病、高血压、高血脂、K+<3.5 mmol/L、TT>18 s、PT<11 s、FIB>4 g/L、APTT>35 s、HCY>15.39μmol/L、T3<1.2 nmol/L、T4<70 nmol/L、TSH<2.75 mU/L、游离T3<2.3 pmol/L、游离T4<10.3 pmol/L为危险因素(OR>1,P<0.05)。结论急性冠脉综合征的危险因素有心血管疾病、糖脂代谢异常、高尿酸、低钾、同型半胱氨酸指标升高、凝血功能异常、甲状腺功能异常及心肌损伤。Objective To analyze risk factors for acute coronary syndromes.Methods A total of 855 patients with acute coronary syndrome who received consultation and treatment in Suqian First People’s Hospital from January 2020 to December 2022 were included in the disease group.During the same period,855 volunteers who received physical examination in our hospital were included in the control group.The general data,past medical history,blood indices and living habits of the two groups were collected and compared.Logistic regression analysis was performed to analyze the relevant factors affecting acute coronary syndromes.Results Multivariate Logistic regression found that BMI≤23.9kg/m^(2),dietary habits of light nutrition,smoking index≤400,and daily alcohol intake≤15g were the protective factors for acute coronary syndrome(OR<1,P<0.05);while coronary artery disease,diabetes mellitus,hypertension,hyperlipidemia,K+<3.5mmol/L,thrombin time(TT)>18s,prothrombin time(PT)<11s,fibrinogen(FIB)>4g/L,activated partial thromboplastin time(APTT)>35s,homocysteine(HCY)>15.39μmol/L,triiodothyronine(T3)<1.2nmol/L,thyroxine(T4)<70nmol/L,thyroid-stimulating hormone(TSH)<2.75mU/L,free T3<2.3pmol/L,and free T4<10.3pmol/L were risk factors(OR>1,P<0.05).Conclusion Risk factors for acute coronary syndrome include cardiovascular disease,abnormalities of glucose and lipid metabolism,high uric acid,low potassium,elevated homocysteine markers,coagulation abnormalities,abnormalities of thyroid function,and myocardial injury.

关 键 词：40岁以下 急性冠脉综合征 Logistic回归分析模型 危险因素 

分 类 号：R543.3[医药卫生—心血管疾病]