当归四逆汤加减联合中医定向透药治疗椎动脉型颈椎病的临床研究  

Clinical study of modified Danggui Sini Decoction combined with traditional Chinese medicine directional penetration in the treatment of cervical spondylosis of vertebral artery type

作　　者：王静 肖斌 黄明儒 张一鸣 洪敏 WANG Jing;XIAO Bin;HUANG Mingru;ZHANG Yiming;HONG Min(The First Department of Internal Medicine,Jingdezhen Hospital of Traditional Chinese Medicine,Jiangxi Province,Jingdezhen 333000,China;Department of Traditional Chinese Medicine,Duchang Puren Orthopedic Hospital Co.,LTD.,Jiangxi Province,Jiujiang 332600,China)

机构地区：[1]江西省景德镇市中医医院内一科,江西景德镇333000 [2]江西省都昌谱仁骨科医院有限公司中医科,江西九江332600

出　　处：《中国当代医药》2024年第29期100-103,共4页China Modern Medicine

基　　金：江西省中医药管理局科技计划项目(2022B556)。

摘　　要：目的探讨当归四逆汤加减联合中医定向透药治疗椎动脉型颈椎病(CSA)的临床效果。方法选取2022年7月至2023年7月景德镇市中医医院收治的80例CSA患者作为研究对象,采用随机数字表法分为西药组和中西医特色治疗组,每组各40例。西药组采用盐酸氟桂利嗪胶囊治疗,中西医特色治疗组在西药组的方法基础上,采用当归四逆汤加减联合中医定向透药治疗。评估两组患者的临床疗效,并比较两组患者治疗前与治疗14d后的颈椎症状与功能[颈性眩晕评估量表(ESVC)]、中医症状积分以及颅内椎-基底动脉血流情况[颅内椎-基底动脉的收缩期峰值血流速度(Vp)及舒张末期峰值血流速度(Vd)]。结果中西医特色治疗组的临床疗效优于西药组,总有效率(95.00%)高于西药组(75.00%),差异有统计学意义(P<0.05)。治疗前,两组患者的ESVC评分、中医症状总积分和颅内椎-基底动脉Vp、Vd比较,差异无统计学意义(P>0.05)。治疗后,两组患者的ESVC评分均高于本组治疗前,且中西医特色治疗组的ESVC评分高于西药组,差异有统计学意义(P<0.05);治疗后,两组患者的中医症状总积分均低于本组治疗前,且中西医特色治疗组的中医症状总积分低于西药组,差异有统计学意义(P<0.05);治疗后,两组患者的颅内椎-基底动脉Vp、Vd均快于治疗前,中西医特色治疗组的颅内椎-基底动脉Vp、Vd均快于西药组,差异有统计学意义(P<0.05)。结论当归四逆汤加减联合中医定向透药治疗CSA疗效显著,能改善颈性眩晕症状与功能,缓解相关中医症状严重程度,促进颅内椎-基底动脉血流速度提高。Objective To explore the clinical effect of modified Danggui Sini Decoction combined with traditional Chinese medicine directional penetration in the treatment of cervical spondylosis of vertebral artery type(CSA).Methods A total of 80 patients with CSA admitted to Jingdezhen Hospital of Traditional Chinese Medicine from July 2022 to July 2023 were se-lected as the research objects,and they were divided into western medicine group and traditional Chinese and western medicine characteristic treatment group by random number table method,with 40 cases in each group.The western medicine group was treated with Flunarizine Hydrochloride Capsules,and the traditional Chinese and western medicine characteristic treatment group was treated with Danggui Sini Decoction combined with traditional Chinese medicine directional penetration on the basis of the methods of the western medicine group.The clinical efficacy of the two groups was evaluated,and the cervical spine symptoms and function(evaluation scale for cervical vertigo[ESVC]),traditional Chinese medicine symptom score and intracranial vertebrobasilar artery blood flow(intracranial vertebrobasilar artery peak systolic blood flow velocity[Vp]and end peak end-diastolic blood velocity[Vd])were compared between the two groups before treatment and 14 days after treatment.Results The clinical efficacy of the traditional Chinese and western medicine characteristic treatment group was better than that of the western medicine group,and the total effective rate(95.00%)was higher than that of the western medicine group(75.00%),and the differences were statistically significant(P<0.05).Before treatment,there were no statis-tically significant differences in ESVC score,total tradi-tional Chinese medicine symptom score,Vp and Vd of in-tracranial vertebrobasilar artery between the two groups(P>0.05).After treatment,the ESVC scores of the two groups were higher than those before treatment,and the ESVC score of the traditional Chinese and western medicine characteristic treat-ment grou

关 键 词：当归四逆汤加减 中医定向透药 椎动脉型颈椎病 颈椎症状与功能 颅内椎-基底动脉血流情况 

分 类 号：R274[医药卫生—中医骨伤科学]