口服与肌内注射咪达唑仑用于小儿疝气手术超前镇静中的麻醉效果及对焦虑情况的影响  

Anesthetic Effect of Oral and Intramuscular Injection of Midazolam for Preemptive Sedation in Pediatric Hernia Surgery and the Influence on Anxiety

作　　者：陈友艳 邹飞 何宗洪 CHEN Youyan;ZOU Fei;HE Zonghong(Department of Anesthesia,Yinjiang Autonomous County People's Hospital in Tongren City,Tongren,Guizhou,555200,China)

机构地区：[1]铜仁市印江自治县人民医院麻醉科,贵州铜仁555200

出　　处：《中外医疗》2024年第25期115-118,共4页China & Foreign Medical Treatment

摘　　要：目的探讨分析口服与肌内注射咪达唑仑用于小儿疝气手术超前镇静中的麻醉效果及对焦虑情况的影响。方法随机选取2023年6月—2024年2月铜仁市印江自治县人民医院收治的60例疝气手术患儿为研究对象,均接受超前镇静,以不同麻醉方式分为A组(口服0.25~0.5 mg/kg咪达唑仑)和B组(肌内注射咪达唑仑),各30例,比较分析两组麻醉效果、焦虑评分、术中体动次数、术毕苏醒时间、不良反应发生率。结果镇静前(T0)、镇静10 min后(T1)、镇静30 min后(T2),A组与B组的平均动脉压、血氧饱和度水平比较,差异无统计学意义(P均>0.05)。T0~T2时,A组改良耶鲁术前焦虑评分与B组相比,差异无统计学意义(P均>0.05)。A组患儿术中体动次数、术毕苏醒时间与B组比较,差异无统计学意义(P均>0.05)。A组不良反应发生率为5.00%(2/40),低于B组的20.00%(8/40),差异有统计学意义(χ^(2)=4.114,P<0.05)。结论在小儿疝气手术超前镇静中口服与肌内注射咪达唑仑均能获得理想的麻醉效果,改善患儿焦虑情况,且口服咪达唑仑不良反应较少、安全性较高。Objective To investigate and analyze the anesthetic effect of oral and intramuscular injection of midazolam for preemptive sedation in pediatric hernia surgery and its effect on anxiety.Methods From June 2023 to February 2024,a total of 60 children with hernia surgery were admitted to the Yinjiang Autonomous County People's Hospital in Tongren City were randomly selected as the research objects,all of whom received advanced sedation.They were di⁃vided into group A(oral administration of 0.25-0.5 mg/kg midazolam)and group B(intramuscular injection of mid⁃azolam)according to different anesthesia methods,with 30 cases in each group.The anesthetic effect,anxiety score,the number of body movents during operation,recovery time after operotion and incidence of adverse reactions were compared between the two groups.Results Before sedation(T0),10 min after sedation(T1)and 30 min after sedation(T2),there were no statistically significant differences in mean arterial pressure and blood oxygen saturation between group A and group B(all P>0.05).At T0-T2,there were no statistically significant differences in the Modified Yale Preoperative Anxiety Scale-short Form score between group A and group B(all P>0.05).There were no significant dif⁃ferences in the number of body movents during operation and recovery time after operotion between group A and group B(all P>0.05).The incidence of adverse reactions in group A was 5.00%(2/40),which was lower than 20.00%(8/40)in group B,and the difference was statistically significant(χ^(2)=4.114,P<0.05).Conclusion In the preemptive sedation of pediatric hernia surgery,both oral and intramuscular midazolam can obtain ideal anesthetic effect,improve the anxi⁃ety of children,and oral midazolam has fewer adverse reactions and higher safety.

关 键 词：肌内注射 咪达唑仑 小儿疝气手术 超前镇静 焦虑 

分 类 号：R614[医药卫生—麻醉学]